Moringa Supplementation for Improved Milk Output

Investigating the Effect of Moringa Oleifera Leaf Powder on Breastmilk Quantity and Quality: a Double Blinded Randomized Placebo-controlled Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05333939

Enrollment

Registered

2022-04-19

Start date

2022-05-17

Completion date

2024-08-03

Last updated

2024-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breastfeeding

Keywords

maternal and child health

Brief summary

The overall objective is to obtain preliminary data on the effect of Moringa oleifera leaf supplementation (moringa) at 4g daily for four weeks compared to placebo to improve human milk quantity and quality and infant health. Hypothesis: Four grams of moringa daily by mouth compared to placebo will increase breastmilk output and percent of mother's own milk consumed by infant.

Interventions

DIETARY_SUPPLEMENTMoringa leaf powder

capsule ingestion

OTHERPlacebo

capsule ingestion

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Intervention model description

placebo controlled randomized controlled trial

Eligibility

Sex/Gender

ALL

Age

0 Months to No maximum

Healthy volunteers

Yes

Inclusion criteria

Mom YES: * willing to breastfeed or pump for one week * willing to complete study activities (at minimum measure 24 hour pumped volume at start and end of capsules, take capsules daily, and answer questions) * has access to breastpump (in hospital and/or home) * English speaking * 18 years or older * Gave birth between 2-6 weeks prior to study start NO: * taking metoclopramide (trade name Reglan) currently or within 2 weeks of enrollment * taking moringa regularly or within 2 weeks of enrollment * breast surgery (amplification, reduction, or other) * breast condition: Insufficient Glandular tissue * unprescribed or street drug use at any point in pregnancy, or enrolled in rehab program or receiving addiction therapy * refuses to take 4 capsules twice daily within 2 days of study start * wishes to withdraw within 2 days of study start Infant YES: * 28-36 and 7 weeks gestation (ie 37 weeks is too old) * 2-6 weeks old * singleton birth NO: · any condition where breastmilk is clinically contraindicated

Design outcomes

Primary

Measure	Time frame	Description
Milk output	7 days	24 hour milk output at 7 days

Secondary

Measure	Time frame	Description
% mother's own milk consumed by infant	7 days	% of mother's own milk (over total enteral nutrition) consumed by infant at 7 days

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026