Virtual Reliability System for Visual Spatial Attention Evaluation in Stroke Patients

Application of a Virtual Reliability System in the Evaluation of the Visual Spatial Attention in Stroke Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05332964

Enrollment

Registered

2022-04-18

Start date

2025-03-01

Completion date

2025-12-31

Last updated

2026-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neglect, Hemispatial, Stroke Sequelae

Keywords

attention, hemineglect, virtual reality, reaction time

Brief summary

The researchers designed a software based on a head-mounted displays for virtual reality (HMD-VR) to evaluate the reaction time to stimuli presented at right or left visual field. The study will recruit 100 stroke patients with hemisphere lesions (50 patients for right and left each) and 100 age-matched healthy controls. The participants will conduct a simple reaction time task in VR, with stimuli designated in the left or right hemi-field. The stroke patients will also received traditional tests for hemi-neglect. Test-retest reliability of the assessment will be conducted in a subset of the control group. The stroke patients will be followed in 3-4 weeks.

Detailed description

The researchers designed a software based on a head-mounted displays for virtual reality (HMD-VR) to evaluate the reaction time to stimuli presented at right or left visual field. The study will recruit 100 stroke patients with hemisphere lesions (50 patients for right and left hemisphere each) and 100 age-matched healthy controls. The participants will conduct a simple reaction time task in VR, with stimuli designated in the left or right hemi-field. The stroke patients will also receive traditional tests for hemi-neglect. The researchers will also collect the demographic data, cognition function and daily activity function. Test-retest reliability of the assessment will be conducted in a subset of the control group. The stroke patients will be followed in 3-4 weeks. The researchers will compare the results of a traditional hemi-neglect tests and VR-based tests and their changes in two occasions.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

for stroke patients: 1. aged at least 20 years old 2. diagnosed with stroke involving unilateral MCA and ACA territory 3. with unilateral upper limb with normal function 4. neurologically and medically stable. Inclusion criteria for control group: 1\) healthy adults, age-matched to stroke patients

Exclusion criteria

for both groups: 1. with history of neurological or psychiatric conditions other than stroke; 2. significant cognitive or speech problems that cause difficulties to cooperate with testing; 3. significant visual problems (such as color blindness, visual loss, cataract, glaucoma or other major eye condition) 4. upper limb musculoskeletal disorders to cause difficulties to use the keyboard or controller; 5. history of seizure, vestibular dysfunction or vertigo 6. can't tolerate HMD-VR

Design outcomes

Primary

Measure	Time frame	Description
reaction time	4 weeks	reaction time to the stimuli presented in the right or left hemi-field with VR software
hemineglect tests	4 weeks	Paper-based behavior inattention test (BIT)

Secondary

Measure	Time frame	Description
ADL	4 weeks	activities of daily living function evaluated by barthel index
cognition	4 weeks	using Montreal Cognitive Assessment (MoCA)
cybersickness	1 day	using Simulator Sickness Questionnaire (SSQ)

Countries

Taiwan

Contacts

PRINCIPAL_INVESTIGATORHuey-Wen Liang, MD

National Taiwan University

Outcome results