Coronavirus Infections, Critical Illness
Conditions
Brief summary
Corona virus disease has been a pandemic since its beginning. The problem has scaled to break health care system of multiple countries. One of the prime strategy of preventing this disease has been large mass scale vaccination campaign ongoing worldwide. No vaccine has been proven to 100 percent effective in preventing the infection with coronavirus disease so far. The investigators are conducting a study comparing outcome among vaccinated and unvaccinated population admitted to critical care unit of civil services hospital, Kathmandu , Nepal .
Detailed description
Coronavirus disease has been a pandemic since its beginning. The problem has scaled up and health care system of multiple countries have reached to a breaking point . One of the prime strategy of preventing this disease has been large mass scale vaccination campaign ongoing worldwide. No vaccine has been proven to 100 percent effective in preventing the infection with coronavirus disease so far. The investigators are conducting a study comparing difference in outcome with regard to mortality and length of critical care unit stay among vaccinated and unvaccinated population admitted to critical care unit of civil services hospital , Kathmandu , Nepal. Since different groups of population received different vaccine according to age profession and other factors investigators are trying to study the effectiveness of vaccine with regards to type of vaccine.
Interventions
DRUGVaccine
patients who have received vaccine against coronavirus disease infection
Sponsors
Civil Service Hospital of Nepal
Study design
Observational model
CASE_CROSSOVER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
patients proven to have covid 19 infection patients more than 18 years of age patients admitted to critical care unit
Exclusion criteria
* patient below 18 years of age patients who do not have covid 19 infection
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mortality | within 12 weeks from the date of critical care unit admission | the primary outcome to be measured will be difference in mortality among two groups (vaccinated and unvaccinated) of coronavirus infected patients admitted in critical care unit |
| length of icu stay | with 12 weeks from the date of critical care unit admission | difference in length of stay between vaccinated and unvaccinated population admitted to critical care unit after being infected with coronavirus disease |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| difference in mortality due to associated co-morbidity | within 24 weeks form the date of critical care unit admission | difference in mortality due to associated co-morbidity will be compared among both the group (vaccinated and unvaccinated) |
Contacts
Primary ContactDeepak Bhandari, MD
Backup ContactAalok Parajuli, mbbs
Outcome results
None listed