Allergic Rhinitis, Asthma, Atopic Dermatitis, Bronchiectasis Adult, Bronchitis, Chronic Obstructive Pulmonary Disease(COPD), Eczema, Emphysema, Urticaria
Conditions
Keywords
Asthma, Allergic Rhinitis, Climatotherapy, Chronic Obstructive Pulmonary Disease(COPD), Atopic Dermatitis, Climate, Environment
Brief summary
To investigate the Influence of Climatic and Environmental Factors on Respiratory or Allergic Diseases in Sanya.
Detailed description
The study is an observational research, which will recruit the community migratory old people and children at school using cluster sampling in Sanya by Sanya Maternal and Child Health Care Hospital (Sanya Women and Children's Hospital). Sanya Central Hospital(Hainan Third People's Hospital) and People's Hospital of Sanya will assist to diagnose old people disease. The data of climate and environment will be obtained from Sanya Meteorological Administration and Sanya Municipal Ecology and Environment Bureau. 1. The primary purpose is to investigate the influence of the unique tropical climate and environmental factors on the migratory old people with diseases such as asthma, allergic rhinitis, COPD or atopic dermatitis in Sanya from northern China, and to provide scientific evidence for publicity of the tourism and the health care industry. 2. The secondary purpose is to investigate prevalence and risk factors of asthma, allergic rhinitis and atopic dermatitis among children in Sanya, which will provide a base for prevention and control strategies. 3. The third purpose is to retrospectively analyze the influence of climate and environmental factors in Sanya on children with asthma, allergic rhinitis and atopic dermatitis in the past decade, and a comparative analysis of the incidence on children in Sanya and Shanghai.
Interventions
OTHERClimate and environment in Sanya
Sanya have unique island climate and environment campared with the north of China, with a feature of warm, moist and long-sunshine.
Sponsors
Shanghai Jiao Tong University School of Medicine
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
3 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* 50-80 years-old migratory people with asthma, allergic rhinitis, COPD or atopic dermatitis from northern China; * 3-12 years-old children in Sanya; * Agree to participate this study.
Exclusion criteria
* Disagree to participate this study; * Having other respiratory diseases which can influence airflow, such as lung cancer, tuberculosis, pneumonia, bronchiectasis, etc; * Inability to understand the study procedures or inability/reluctance to answer questionnaire judged by the investigator.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The difference of migratory old people with asthma, COPD, allergic rhinitis or atopic dermatitis between winter-spring season in tropical Sanya, Hainan Island and summer-autumn season in northeast China. | 3 year | The asthma, COPD, allergic rhinitis or atopic dermatitis will be diagnosed and assessed through history of diseases and questionnaire.. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Asthma life quality of migratory old people with asthma. | 1-3 year | Quality of life is assessed through questionnaires of Asthma Quality of Life Questionnaire (AQLQ). |
| Lung function of migratory old people with asthma or COPD. | 1-3 year | Lung function is assessed through simple lung function test using spirometry. |
| The respiratory function of migratory old people with COPD. | 1-3 year | Lung function is assessed through Saint George Respiratory Questionnaire (SGRQ). |
| Asthma control of migratory old people with asthma. | 1-3 year | Quality of life is assessed through questionnaires of Asthma Control Questionnaire (ACQ) . |
| Inflammatory factors will be detected in migratory old people with asthma, allergic rhinitis or atopic dermatitis. | 1-3 year | Inflammatory factors such as esophageal granulocytes and eosinophils will be detected to assess inflammatory status of the migratory old people. |
| The change of asthma incidence rate in migratory old people . | 1-3 year | Diagnosis and severity grading of asthma is based on the American Thoracic Society or the National Heart, Lung, and Blood Institute guidelines. |
| Allergens will be detected in migratory old people with asthma, allergic rhinitis or atopic dermatitis. | 1-3 year | Veinal blood was extracted to detect allergens. |
Countries
China
Contacts
Primary ContactShijian Liu, Ph.D
Outcome results
None listed