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Transurethral Resection Versus Transurethral Enucleation of the Prostate: Prospective Randomized Study

Transurethral Resection Versus Transurethral Enucleation of the Prostate: Prospective Randomized Study

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05330156
Acronym
Prostate
Enrollment
58
Registered
2022-04-15
Start date
2022-04-30
Completion date
2024-04-30
Last updated
2022-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

BPH

Brief summary

TUERP technique could be used in prostates of all sizes with the same safety and efficacy size independent procedure . TUERP could be performed using the bipolar system only ,with or without the use of morcellator.

Detailed description

Transurethral resection of the prostate (TURP) was first done in the 1920s. Since then, TURP has been considered as the gold standard treatment for BPH . However, its relatively high complication rate and postoperative recurrence necessitates further modification in the surgery technique .The resected adenomas have been reported to recur in up to 15% of cases that need a repeat surgical intervention, even by experienced surgeons in high-volume centers . Before the era of TURP, simple open prostatectomy was the mainstay of surgical therapy. However, open simple prostatectomy has high risk of considerable intraoperative bleeding requiring transfusion. The lower abdominal incision done in open prostatectomy may result in significant postoperative pain, an extended recovery period and longer hospital stay, with greater morbidity and a perioperative mortality rate of 0.2%. In addition, TURP for large prostatic adenomas causes significantly much more bleeding with clot retention as compared to simple open prostatectomy, it also need a longer operative time, which leads to increased risk of TUR syndrome with subsequent morbidity . A new technique in which transurethral enucleation and resection of the prostate (TUERP) was developed and adopted to replicate the open enucleation of prostatic adenomas in an endoscopic way. This will combine the benefits of complete prostate enucleation in a minimally invasive technique . prostate enucleation by laser currently used as minimally invasive and save alternative to TURP, but still has not been widely accepted for some reasons, including high cost and prolonged learning curve. TUERP technique could be used in prostates of all sizes with the same safety and efficacy size independent procedure . TUERP could be performed using the bipolar system only ,with or without the use of morcellator

Interventions

\- After an initial cysto-urethroscopy assessment done, Transurethral resection of the prostate is performed using the bipolar system with normal saline irrigation, under spinal or general anesthesia.

PROCEDUREtransurethral enucleation of prostate

After an initial cysto-urethroscopy assessment done, transurethral enucleation of prostate is performed using the bipolar system with normal saline irrigation, under spinal or general anesthesia.

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
MALE
Healthy volunteers
No

Inclusion criteria

* -Patients aging from 50 to 80 years old who are diagnosed with clinical symptomatic BPH. * The patients have clear indi¬cation for endoscopic surgery (according to the guidelines). * Clinically fit patients for surgery. * Signed an informed consent.

Exclusion criteria

* Prostate cancer Previous urethral or prostate surgery Neurogenic bladder Urethral stricture Poor general condition of the patient

Design outcomes

Primary

MeasureTime frameDescription
Time of operationintraoperative (from the start of resection or enucleation till the fixation of urethral catheter)time used for resection or enucleation and resection of the prostate

Countries

Egypt

Contacts

Primary ContactAhmed F Hassan, Master
ahmedfarahat358@gmail.com01069569946
Backup ContactAHMED F HASSAN
ahmedfarahat358@gmail.com01156522620

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026