Parkinson Disease
Conditions
Keywords
Parkinson Disease, Rehabilitation, Postural Transfers
Brief summary
This observational trial aims to evaluate the effect of Rehabilitation on Postural Transfers (PTs) in subjects affected by Parkinson Disease. The PTs are evaluated by an inertial sensor (a device composed by an accelerometer, a gyroscope and a magnetometer) attached to the subjects. The data obtained by the inertial sensor are kinematic (e.g. acceleration and angular speed) and spatiotemporal parameters (e.g. time to completion and velocity). Additional clinical evaluations are carried out at the beginning and end of the rehabilitative intervention.
Interventions
OTHERRehabilitation
Intervention focused on balance, gait and postural transfers rehabilitation. 20 session of 90 minutes (60 minutes of physiotherapy and 30 minutes of occupational therapy), 2 times a week, for 10 weeks.
Sponsors
Fondazione Don Carlo Gnocchi Onlus
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Subjects with Idiopathic Parkinson's Disease; * Subjects should be in a positive therapeutic window or in the ON phase during the evaluations; * Subjects must be able to walk at least 10 meters independently with or without any walking aid
Exclusion criteria
* Non-clinically stable subjects; * Subjects in OFF phase during the evaluations; * Other neurological conditions (e.g. stroke, peripheral neuropathies, etc.); * Other pathologies that can negatively influence the subject's walking ability (e.g. surgery at the lower limbs in the previous 6 months, important deformities at the lower limbs, etc.)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of superior-inferior acceleration during Postural Transfers execution | Change from Baseline at 10 weeks | The superior inferior acceleration is measured via an inertial measurement unit attached to the back of the patient. |
| Change in execution time of Postural Transfers | Change from Baseline at 10 weeks | The execution time is measured via an inertial measurement unit attached to the back of the patient |
| Change of execution velocity of Postural Transfers | Change from Baseline at 10 weeks | The execution velocity is measured via an inertial measurement unit attached to the back of the patient. Specifically the velocity are measured as the Root Mean Square of gyroscope signal. |
| Change of antero-posterior acceleration during Postural Transfers execution | Change from Baseline at 10 weeks | The antero-posterior acceleration is measured via an inertial measurement unit attached to the back of the patient. |
Secondary
| Measure | Time frame |
|---|---|
| Change in Time Up and Go Test | Change from baseline at 10 weeks |
| Change in 10 meter walking test | Change from baseline at 10 weeks |
| Change in Berg Balance Scale Score | Change from baseline at 10 weeks |
| Change in Short-Form 12 score | Change from baseline at 10 weeks |
Countries
Italy
Outcome results
None listed