Nutrition Related Cancer, Radiotherapy Side Effect
Conditions
Keywords
nutrition, radiotherapy, cancer patients
Brief summary
Using randomized control study, explore the effect of novel nutrition education program on the nutrition status and life quality of cancer patients receiving radiotherapy
Detailed description
Weight loss is common among cancer patients, and can be attributed to many causes, including mucositis, inability to ingest or absorb adequate calories because of a problem with the alimentary tract, loss of appetite, and metabolic aberrations. Unintentional weight loss may be associated with decreased quality of life (QOL) and a poorer prognosis. Furthermore, for patients who are already in a catabolic state, the increased metabolic demands associated with anticancer treatment (particularly surgery) further worsen the problem. The novel nutrition program might improve the nutrition status and QOL in cancer patients receiving radiotherapy.
Interventions
PROCEDUREnovel nutrition program
Give nutrition health education every two weeks and regular survey and intervention. The education booklets are made based on the guideline and characteristics of the disease.
Sponsors
Asia University
Taipei Medical University WanFang Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Subject)
Masking description
single blind (Participant)
Intervention model description
single blind (Participant)
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Patients are diagnosed with cancer and receive radiotherapy, especially in head and neck cancer, lung cancer, or esophageal cancer. 2. Patients need nutrition support treatment 3. Informed consent
Exclusion criteria
1. Critical patients or life expectancy \< 12 weeks 2. Patients with severe hepatic cirrhosis, Chronic Obstructive Pulmonary Disease, chronic renal failure, intestinal obstruction, stroke. 3. Unconscious or psychiatric patients 4. Patients with communication problems
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| risk of malnutrition | Week 0, 12 | Nutrition Risk Screening 2002 is used to assess the risk of malnutrition. |
| BMI | Week 0, 12 | Body mass index is a measure of body fat based on height and weight that applies to adult men and women. It equals to weight divided by height square. |
| albumin | Week 0, 12 | level of serum albumin |
| Quality of Life (QOL) | Week 0, 12 | The QOL was measured by the European Organization for Research and Treatment quality of life version 3 questionnaire (EORTC QLQ-C30) simplified Chinese version. It contains five functional scales (physical, role, cognitive, emotional, and social), three symptoms scales (fatigue, pain, and nausea and vomiting), a global health scale, a number of single items assessing additional symptoms commonly reported by cancer patients (dyspnea, appetite loss, insomnia, constipation, and diarrhea) and financial impact of the disease. For most items, four response categories from 1 (not at all) to 4 (very much) are employed; two items (overall health, overall quality of life) have response categories ranging from 1 to 7. A high scale score represents a higher response level. Thus a high score for a functional scale, the global health status or overall QOL represents a high or healthy status or a high QOL; however, a high score for the symptom scales represents a high level of symptom. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| physical function status | Week 0, 12 | Using Eastern Cooperative Oncology Group to assess the physical function. |
| Knowledge-Attitude-Practice | Week 0, 12 | Knowledge Scale composes of 10 questions and 10 scores for each question. Attitude and Practice Scale have 5 questions. Each question is rated as A、B、C. A represents 20 score and B is 10 score. |
Countries
Taiwan
Contacts
Primary ContactSzu-Yuan Wu
Outcome results
None listed