Plasma Immunity of Mild SARS-CoV-2 Omicron and Delta Pandemic in Thailand

The Study of Treatment Outcome and Immunogenicity of mild-to Moderate COVID-19 Patients During the Delta vs. the Omicron Pandemic

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05328479

Enrollment

5181

Registered

2022-04-14

Start date

2021-11-04

Completion date

2022-05-20

Last updated

2022-10-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19

Keywords

COVID-19, antibody, immunity, home isolation, vaccine

Brief summary

The investigators assessed the effect of treatment for COVID and immunity of the volunteers who admitted to the home isolation.

Detailed description

The investigators aimed to assess the effect of treatment for COVID and immunity of the volunteers who admitted to the home isolation. The investigators compared the population between the age groups 12-18 years, 18-45 years and over 45 years to monitor the symptoms of coronavirus patients treated in home isolation and long-term symptoms including factors related to the patient's recovery in the past, present, and future.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

12 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

1. patient with infected with the novel coronavirus disease 2019 (COVID-19) who has been end of self-quarantine at Siriraj Hospital more than 21 days. 2. Thai nationality, able to read and write Thai language 3. able to use telephone and line to communicate

Exclusion criteria

1\. people who received additional vaccination after leaving quarantine before the day of the immunization test

Design outcomes

Primary

Measure	Time frame	Description
Anti-SARS-CoV-2 RBD IgG	Baseline	Anti-RBD IgG (BAU/mL)
Anti-SARS-CoV-2 NP	Baseline	Anti-SARS-CoV-2 NP (PRNT50 titer)
Cycle threshold of the first PCR test	Baseline	Cycle threshold (Ct)

Secondary

Measure	Time frame	Description
Number of vaccine injection	Baseline	Number of vaccine injection
Type of vaccine injection	Baseline	Type of vaccine injection

Countries

Thailand

Outcome results