Liver Metastases
Conditions
Keywords
CT, metastasis, liver
Brief summary
This prospective study aims to perform intra-individual comparison of the image quality between low dose liver CT with deep learning reconstruction and standard dose liver CT with iterative reconstruction in patients with liver metastasis.
Interventions
DIAGNOSTIC_TESTcontrast-enhanced abdomen CT
contrast-enhanced abdomen CT using dual-source CT scanner using A-tube (67% radiation) and B-tube (33% radiation). * full dose CT data (A +B tubes, 100%) are reconstructed with iterative reconstruction (conventional) * low dose CT data (A-tube only, B-tube only) are reconstructed with deep learning commercially available software. * images are reconstructed using full dose (A- & B- tubes) and smaller dose (A-tube only, B-tube only)
Sponsors
Seoul National University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* patients with underlying malignancy and suspicion of liver metastasis * patients with known liver metastasis and on follow-up * AND scheduled for contrast enhanced abdomen CT * signed informed consent
Exclusion criteria
* absolute or relative contra-indication for contrast-enhanced CT * diffuse infiltrative liver lesion or multiple (\> 10) metastases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| liver lesion conspicuity | 6 months after the CT scan | graded on a five-point scale (1-5) with higher score indicates a better conscpicuity. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| liver lesion detectability | 6 months after the CT scan | liver lesion detection rate on standard dose CT and low dose CT by blinded reviewers |
Countries
South Korea
Outcome results
None listed