Sarcopenia
Conditions
Keywords
Sarcopenia, colorectal neoplasm, colorectal surgery, psoas muscles
Brief summary
The purpose of this study is to compare the post-operative course in patients suffering from sarcopenia who had colorectal surgery for cancer. Our primary outcome is the comparaison of the length of hospital stay in sarcopenic and non sarcopenic patients.
Detailed description
Sarcopenia is the loss of muscle mass that occurs usually with aging, but it may have multiple contributing factors, especially related to chronic diseases such as colorectal cancer. When present, sarcopenia is predictive of poor post-operative course. The identification of sarcopenia needs either the identification of low muscle strength, low muscle quantity/quality, or finally a low physical performance. Multiple clinical, biological or radiological tools were proposed. Our purpose is to compare the post-operative outcome of sarcopenic and non sarcopenic patients using a simple, available, reproducible and rapid radiological method, which will help the healthcare professionals to rapidly identify high risk patients for possible complicated and long post-operative course allowing them to take appropriate perioperative measures to reduce the risks.
Interventions
OTHERColectomy with anastomosis of any type
Patient with colonic resection followed by ileocolic, or colo colic, or colorectal, or coloanal anastomosis for cancer by laparoscopy or laparotomy
Sponsors
Hôpital NOVO
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient operated on for colectomy or proctectomy with restoration of continuity for colorectal cancer between 1 January 2020 and 31 December 2021 * Patient who had a CT scan in the 2 months prior surgery * Patient aged 18 years or older
Exclusion criteria
* Patients with inflammatory bowel disease (Crohn disease, haemorrhagic rectocolitis) * Patients with neuromuscular pathology affecting their mobility * Patients who were diagnosed positif to SARS COV 2 before or during hospitalisation * Patients who refuse the collection of their data
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Comparison of the average postoperative length of stay in sacopenic and non-sarcopenic patients | Until discharge from hospital, an average of 30 days | Comparison of the number of post-operative hospital days between the two groups |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Comparison between complication rate in sarcopenic and non sarcopenic patients | At the end of the 30 post-operative days | Measurement of the complication rate according to the Clavien Dindo score (relevant score if greater than or equal to 2, considered severe complication if greater than or equal to 3) between the two groups |
| Assessment of re-hospitalization rate between sarcopenic and non sarcopenic patients | At the end of the 30 post-operative days | Evaluation of the number of hospitalizations of more than 24 hours at 30 days after the operation between the two groups |
| Comparison of the transfer rate to rehabilitation or nursing home center between sarcopenic and non sarcopenic patients | At the end of the 30 post-operative days | Evaluation of the number of transfer to rehabilitation or nursing home center at 30 days after the operation between the two groups |
| Comparison of the length of stay in the rehabilitation center for sarcopenic and non sarcopenic transferred patients | At the end of the 30 post-operative days | Comparison of the number of hospital days for transferred patients between the two groups |
Countries
France
Outcome results
None listed