Knee Osteoarthritis
Conditions
Keywords
OA, Chondratin sulfate, glucosamine, Physiotherapy
Brief summary
to see the effect of glucosamine chondratin sulfate with and without physiotherapy in knee osteoarthritis
Detailed description
it is a randomized control trail to evaluate the effectiveness of glucosamine chondratin sulfate alone and in combination with physiotherapy on knee osteoarthritis
Interventions
control group
COMBINATION_PRODUCTglucosamine chondritin & Physiotherapy
experimental group
Sponsors
Muhammad salman, PT
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Intervention model description
two groups
Eligibility
Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* age \> 50 years with radiographic evidence of mild to moderate knee OA (Kellgren Lawrence grade II & III 20) who met the ACR clinical 21, * radiographic classification criteria or confirmation of mild to moderate radiographic evidence of knee OA from a personal physician * not currently participating in another intervention study
Exclusion criteria
* dementia (Mini-Mental State Examination \[MMSE\]\< 24) * active cancer other than skin cancer * anemia (participants with an hematocrit (HCT)\< 32 (or a hemoglobin below10) were excluded due to possible inability to adequately exercise or the increased potential for increased risk for serious adverse cardiovascular events) * severe renal insufficiency (serum creat\> 2) * hepatic disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| WOMAC | 6 months | higher score means worst patient condition and lower score means better |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| SF-36 | 6 months | higher score means better patient condition and lower score means worst |
Countries
Pakistan
Outcome results
None listed