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Pulmonary Rehabılıtatıon Wıth Non-Small Lung Cancer

Pulmonary Rehabılıtatıon After Chemotherapy In Patıents Wıth Non-Small Lung Cancer

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05320458
Enrollment
11
Registered
2022-04-11
Start date
2022-05-02
Completion date
2022-09-02
Last updated
2022-04-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer, Lung Cancer, Small Cell

Keywords

Lung Cancer, Pulmonary Rehabilitation, Aerobic Exercise, Physiotherapy and Rehabilitation, Oncological Rehabilitation

Brief summary

The aim of our study is to investigate the effects of pulmonary rehabilitation on respiratory tests and quality of life in patients with early and locally advanced NSCLC who received chemotherapy regardless of whether the investigators had undergone surgical treatment.

Detailed description

Patients with lung cancer often have concomitant lung and heart comorbidities that limit their cancer treatment options. For example, in the last prevalence study that included patients with newly diagnosed lung cancer, 73% of whom were men and 53% were women, there was clinically significant COPD. This patient population has shortness of breath, decreased physical capacity, low muscle condiction, and poor exercise tolerance. Pulmonary rehabilitation is an intervention that has a scientific basis and is used systematically, aiming to optimize individual daily functions and health-related quality of life in patients with morbidity due to chronic diseases measured by clinical or physiological methods. The effectiveness of pulmonary rehabilitation is well known in the treatment of patients with COPD and in the perioperative lung transplant preparation period. Studies lead to a significant increase in preoperative pulmonary rehabilitation exercise capacity, dyspnea and health-related quality of life. The aim of our study is to investigate the effects of pulmonary rehabilitation on respiratory tests and quality of life in patients with early and locally advanced NSCLC who received chemotherapy regardless of whether the investigators had undergone surgical treatment. This study was conducted with outpatients who were diagnosed with small cell lung cancer between 2021-2022, who were approved by the oncologist and physical therapist to participate in a physiotherapy and rehabilitation program. Permission for the study was obtained from the Non-Interventional Local Ethics Committee (decision dated 20.11.2018 and numbered 2018/34). The study was conducted in accordance with the Helsinki Declaration of Patient Rights. Individuals were informed about the study and a written informed consent form was signed by the individuals who volunteered to participate. Participants Thirty patients aged 18-65 years in remission were included in the study. Surgery, adjuvant chemotherapy and radiotherapy processes of all patients included in the study were completed. Patients with suspected pregnancy, diagnosis of diabetes mellitus, patients in metastatic period, and patients with acute/chronic infection were excluded from the study. Evaluation The patients' age, gender, height and body weight, medical history and family history information, education status, income level, smoking (pack/year), place of residence, admission to the emergency department in the last year, number of hospital admissions and hospitalizations, and medication used The information was recorded from the patients and their files. Participation of individuals in regular physical activity was questioned. In addition, pre- and post-treatment pain was evaluated using the visual analog scale (VAS). The evaluations applied to the patients in our study; 1. Posture Analysis 2. Normal Joint Movement and Evaluation of Muscle Shortness 3. Muscle Test 4. Six Minute Walking Test 5. Physical Activity Level 6. Dyspnea Severity 7. Quality of Life 8. Fatigue Evaluation Applied Treatments; 1. Respiratory Exercises 2. Walking Training 3. Aerobic exercise training

Interventions

OTHERPulmonary Rehabilitation

1-Pulmonary Rehabilitation: Pulmonary rehabilitation program was applied at 40-60% of submaximal heart rate, 3 days a week for a total of 8 weeks. Diaphragmatic breathing, pursed lip breathing and segmental breathing exercises were practiced with the patients in the company of a physiotherapist. Walking and aerobic exercise training was given.

Sponsors

Hasan Kalyoncu University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

Single group 30 individuals were included in the study. Surgery, adjuvant chemotherapy and radiotherapy processes of all patients included in the study were completed. Patients between the ages of 18-65 and in remission period were included in the study. Patients with suspected pregnancy, diabetes mellitus, metastatic patients, and patients with acute and chronic infections were excluded from the study.

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Between the ages of 18-65, must be in remission. * Surgery, adjuvant chemotherapy and radiotherapy processes must be completed.

Exclusion criteria

* Those with suspected pregnancy * Diabetes mellitus diagnosis * Patients in the metastatic period * Patients with a diagnosis of acute/chronic infection were excluded from the study.

Design outcomes

Primary

MeasureTime frameDescription
Chance from baseline in posture analysis score8 weekPosture score is going to be assess by posture analysis form to determine change from baseline.

Secondary

MeasureTime frameDescription
Physical Activity Level8 weekPhysical Activity is going to be assess by Physical Activity Questionnaire to determine change from baseline.

Countries

Turkey (Türkiye)

Contacts

Primary ContactDeniz Kocamaz, PhD
deniz.erdankocamaz@hku.edu.tr05375735837

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026