Blood Donation
Conditions
Brief summary
we compared the effect of 3 different kinds of liquids (water, Oral Rehydration Salt 3 and white granulated sugar water) intake in Vasovagal Reaction After Whole Blood Donation
Detailed description
Vasovagal reaction is the most common type of blood donation reaction. The main cause of this reaction is the decrease of blood volume. Therefore, fluid supplement before blood donation has been proved to be effective in preventing the vagal reaction after blood donation. It was proved that isotonic (sugar & salt) drink intake before blood donation had a significant effect on reducing vasovagal reaction. However, in 2002, WHO recommended the new reduced osmolarity rehydration formula with better taste. Oral Rehydration Salt 3 has been produced according to WHO formula with standard ingredient and easy to prepare. In addition, in Guangdong culture, sugar water is regarded as a tonic, more easily accepted. So, the aim of our study was to compare the effects of 500 ml water with Oral Rehydration Salt 3, white granulated sugar and conventional recommended water intake prior to blood donation on blood donation reaction after whole blood donation, in order to understand the effect of different liquid supplement on blood donation reaction and the willingness of blood donation again.
Interventions
DRUGOral Rehydration Salts power (iii)
Dissolve 2 packs of Oral Rehydration Salts Power (iii) (5.125g/pack) in 500ml water and let the subjects drink it up in 20 minutes prior to donation.
DIETARY_SUPPLEMENTwater with white granulated sugar
Dissolve 2 packs of Taikoo white granulated sugar (5g/pack) in 500ml water and let the subjects drink it up in 20 minutes prior to donation.
DIETARY_SUPPLEMENTwater
Recommend the subjects to drink up 500ml water in 20 minutes prior to donation.
Sponsors
Guangzhou Blood Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
All blood donors donated whole blood in Guangzhou Blood Center during study. \-
Exclusion criteria
Blood donors who were deferral by blood screening result and other situations. \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| vasovagal reaction rate | 1-3days | vasovagal reaction rate in three groups |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| rate of willingness to donate blood again | 3days | rate of willingness to donate blood again in three groups |
Countries
China
Outcome results
None listed