Urinary Tract Stone, Urosepsis
Conditions
Brief summary
Urosepsis is one of major cause of the overall sepsis leading to high morbidity and mortality, which commonly resulted from urinary tract calculi. The investigator aim to identified the incidence and risk factors of urosepsis in the patients with urinary tract calculi underwent surgical intervention in tertiary-care university hospital.
Detailed description
Sepsis is one of the leading cause of death of hospitalized patients in Thailand. Urosepsis or sepsis which originate from urinary tract infection was reported around 9-31% of the overall sepsis syndrome. Urinary tract calculi requiring surgical procedure was reported as a common cause of urinary tract infection. Therefore, the investigators aimed to identified the incidence and risk factors of urosepsis in the patients with urinary tract calculi underwent surgical intervention in tertiary-care university hospital. Moreover, the patients with sepsis syndrome will be suffered from many complications such as acute respiratory distress syndrome, acute kidney injury, etc. Currently, there were many early waring scores to predict the risk of complications to help promptly treatment and decrease the severity. The investigator would like to compare the systemic inflammatory response syndrome (SIRS) criteria,Modified Early Warning Score (MEWS) and Quick Sequential Organ Failure Assessment (qSOFA) score to the prediction of postoperative complications in this group of patients. The last primary objective of this study is to follow the course of the patients diagnosed as urosepsis if they had been treated properly according to the sepsis bundle guideline and their outcome.
Interventions
None listed
Sponsors
Mahidol University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
\- Adult patients with urinary tract calculi requiring surgical procedure
Exclusion criteria
\- Incomplete data
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rate of urosepsis diagnosis | 7 days after surgery | According to urine exam and SIRS criteria of sepsis |
| Date of urosepsis diagnosis | 7 days after surgery | date of diagnosis of urosepsis |
| Mortality rate | 30 days after surgery | Number of deceased patient after surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Rate of mechanical ventilation requirement | 7 days after surgery | Number of patient required mechanical ventilation support |
| Rate of re-operation | 7 days after surgery | Number of patients require second procedure at the same admission |
| Length of stay | 7 days after surgery | * hospital stay * intensive care unit stay |
| Rate of renal replacement therapy requirement | 30 days after surgery | Number of patients require renal replacement therapy |
| Prevalence of acute kidney injury | 30 days after surgery | According to KDIGO criteria |
| Rate of intensive care unit admission | 7 days after surgery | Number of patients required ICU admission |
| Rate of blood transfusion | 7 days after surgery | Amount of blood transfusion in unit during admission |
Countries
Thailand
Outcome results
None listed