Anxiety, Cortisol Excess, Environmental Exposure, Epigenetic Disorder, Natural Killer Cell Cytokine Production, Stress, Psychological
Conditions
Keywords
Forest therapy, Nature therapy, Cortisol, Psychological stress, Physiological stress, Anxiety, Blood pressure, Natural Killer, DNA Methylation
Brief summary
Recent studies on health personnel in Colombia have evidenced the considerable increase in the levels of stress and anxiety, among other psychological disorders, as a product of the COVID-19 pandemic that is being experienced since 2019 and that implies a greater demand for attention from the affected citizens, with the consequent work overload and tension due to the risk of contagion. Thus, the present work will allow the generation of new knowledge in relation to the benefits of Vitamin N therapy in Colombia; which can contribute quickly and effectively to the reduction of stress levels, anxiety, insomnia, and depression in individuals, when compared with conventional interventions and result in possible benefits such as the reduction of health problems such as obesity, diabetes, high blood pressure, and diseases associated with the immune system.
Interventions
OTHERImmersion therapy in nature - Vitamin N
Usual therapy group The first saliva sample will be taken upon awakening to determine cortisol concentration. At their workplace, they will be asked to remain seated and silent for 3 minutes, the following will be taken: blood pressure, heart rate, psychological instruments (stress-anxiety), blood sample. Group 2A and Group 2B In the natural environment, a saliva sample will be taken upon awakening to determine cortisol concentration. After arrival at the site, they will be asked to remain seated and silent for 3 minutes, the following will be taken: blood pressure, heart rate, psychological instruments (stress-anxiety), blood sample. The first phase is a session of observation of the site for 15 minutes. A slow, unhurried walk will be performed for 1 hour and 45 minutes. The order of activities (sitting and walking) will be established to ensure reliability of physiological measurements.
Sponsors
Jeadran N. Malagón-Rojas
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Intervention model description
Parallel intervention evaluation study that will consider two interventions; the conscious immersion therapy in nature (Vitamin N) and the usual intervention designed by the company for psychosocial risk reduction.
Eligibility
Sex/Gender
ALL
Age
18 Years to 62 Years
Healthy volunteers
Yes
Inclusion criteria
* Persons over 18 years of age * Health care workers * Prioritized by the psychosocial risk program * Complete vaccination schedule for COVID-19
Exclusion criteria
* Undergraduate students in the area of health sciences * Pregnant women * Allergies or sensitivity to the intervention * Workers who consume immunosuppressants or corticosteroids * Workers diagnosed with any type of disease or who have undergone chemotherapy or radiotherapy treatment during the last year * Persons who have had exposure to X-rays in the last 6 months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change Psychological stress measurement scale levels | Three times for 6 months | Determination of a score of the level of occupational stress through different |
| Concentration of Cortisol in saliva | 1 time per month for 6 months | Saliva samples from each subject will be obtained with the Salivette device during each day of the intervention. |
| Outcome Measures in Arterial pressure levels | 4 time per month for 6 months | Blood pressure in mm Hg before and after surgery |
| Outcome Measures in Heart rate levels | 4 time per month for 6 months | Determination by digital sphygmomanometers |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Natural Killer | 1 time per month for 6 months | Proportion of natural killer cells by flow cytometry. |
| Beck Anxiety Inventory levels | Three times for 6 months | Determination of a score of the level of anxiety through different items taken into account in this instrument. |
| NR3C1 and FKBP5 gene methylation. | Two times for 6 months | Percentage of methylation of NR3C1 and FKBP5 genes. |
| Pittsburgh Sleep Quality levels | Three times for 6 months | Determination of a sleep quality score through different items taken into account in this instrument. |
Countries
Colombia
Outcome results
None listed