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Resistance Training in Type 1 Diabetes Mellitus

Resistance Training Methods Impact On Glycemic Excursion and Metabolic Pathways in Type 1 Diabetes Mellitus

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05315037
Enrollment
15
Registered
2022-04-07
Start date
2023-08-01
Completion date
2025-12-30
Last updated
2024-05-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 1 Diabetes

Keywords

Resistance Training in type 1 diabetes

Brief summary

The purpose of this study is to learn how different resistance training programs affects blood sugar in young athletes with T1DM.

Detailed description

Strength and condition training to improve sport performance has been greatly emphasized over the past 20 years. Formal strength and conditioning (S&C) programming is performed by S&C coaches who are educated in the field of exercise program with the intentions to bring about particular athletic adaptations through exercise. S&C programs, previously limited to programs at the college and professional level, are now commonly seen in secondary school athletic programs. With such broad adoption, many athletes that manage chronic diseases, such as type 1 diabetes mellitus, are exposed to elements of these programs. Diabetes mellitus impacts more than 10% of the United States population. Of these, 5.2% have identified type 1 diabetes mellitus (T1DM) which includes approximately 210,000 individuals under the age of 20. In addition to insulin and dietary management, exercise and physical activity is recommended as an important therapeutic tool for most patients with T1DM. Physical activity has been shown to significantly improve glycemic control in individuals with diabetes. Additional benefits of exercise include improved cardiovascular fitness, muscle strength, insulin sensitivity and blood glucose control. S&C programs offer benefits to those living with T1DM as different exercises can be tailored to preserve health. However, there are no exercise prescription or guidelines specifically for adolescent athletes diagnosed with type 1 diabetes participating in strength and conditioning programs. Furthermore, there is no available data that states the predictability of glucose response and insulin needs to any of the specific strength and conditioning goals. Objective: To assess the impact of different strength and conditioning programming on glycemic control in athletes with T1DM. Primary Aim: Assess glucose response to different resistance training methods. Secondary Aims: To assess for correlation between lactate and glucose using different resistance training methods.

Interventions

OTHERResistance Training

Bench press: Exercise performed with participant lying supine with hands in prone position. Barbell is lowered vertically from fully extended elbow position to sternum, then returned to starting position. Barbell will be weighted with plates dependent on their strength and workout demands. Deadlift: Consists of gripping bar while in a squat position. Extension of ankles, knees, and hips while gripping the bar brings the weight up until joints are locked completing the exercise concentric portion. The eccentric lowering of the weight follows and consists of flexion of joints. Seated overhead press machine: This multi-joint exercise, deltoid and trapezius are the prime movers and triceps are secondary movers, with hands on the grips and a position allowing back and buttocks to be completely supported. They push against a load vertically until glenohumeral joint fully extends, then load is returned to starting position and process continues until all repetitions desired are achieved

Sponsors

Norton Healthcare
CollaboratorOTHER
University of Louisville
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE

Intervention model description

Blood glucose and lactate measurements will be collected prior to any physical activity, post workout, and then 10- and 20-minutes post workout. Using a standard lancet device, capillary blood glucose values will be obtained using a Contour Next Glucometer.

Eligibility

Sex/Gender
ALL
Age
13 Years to 17 Years
Healthy volunteers
No

Inclusion criteria

* ≥ 13 years of age * ≥2 years from date of T1DM diagnosis * Prior exposure to strength and conditioning * HbA1C ≤ 10% * Actively utilizing continuous glucose monitoring for diabetes management

Exclusion criteria

* Physical limitation that may impede ability to complete study procedures * Non-English-speaking individual

Design outcomes

Primary

MeasureTime frameDescription
Assess glucose response to different resistance training methods3 monthsBlood glucose

Secondary

MeasureTime frameDescription
To assess for correlation between lactate and glucose using different resistance training methods3 monthsBlood glucose, lactate

Countries

United States

Contacts

Primary ContactBrad J Thrasher, DO
bjthra01@louisville.edu5025883400
Backup ContactSarah P King, BS,BA
slpenn03@louisville.edu5026292721

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026