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Analgesia Nociception Index for Pain Monitoring in Intensive Care Units

Analgesia Nociception Index for Pain Monitoring in Intensive Care Units

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05313789
Enrollment
180
Registered
2022-04-06
Start date
2022-04-11
Completion date
2022-06-06
Last updated
2022-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intensive Care Unit Syndrome, Pain, Stress Related Disorder

Keywords

Analgesia Nociception Index, Intensive Care Unit, Pain Monitoring

Brief summary

The aim of this study is to examine the usability of ANI in patients who will be treated in intensive care unit.

Detailed description

The aim of this study is to examine the usability of Analgesia Nociception Index in patients who will be treated in intensive care unit ( a- Cardiovascular b- surgical c- internal diseases), mechanically ventilated and lacking communication. The investigators will examine whether the positive inotropic/vasoconstrictor agents will have any effect on Analgesia Nociception Index.

Interventions

Monitorization of Analgesia Nociception Index in Intensive Care Patients

Sponsors

İstanbul Yeni Yüzyıl Üniversitesi
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Intensive Care Cardiovascular Patients Group 1 - Patients aged from 18 to 80 years, scheduled for elective isolated coronary bypass graft (CABG) for 2-4 vessel disease, without any perioperative complications, and who were postoperatively monitored via the analgesia nociception index in the cardiovascular intensive care will be included. * Intensive Care Internal Diseases Group 2 - Patients aged from 18 to 80 years, intubated or tracheostomized, In mechanical ventilation with Pressure-Controlled Ventilation mode, under perfusion neuromuscular blocker, Normothermic, non-cooperative and/or sedated and neuromuscular blocker * Intensive Care Patients (Obese) Group 3 - Post Bariatric surgery, over 40 BMI

Exclusion criteria

* Intensive Care Cardiovascular Patients Group 1 Patients who required emergency surgery, had significant preoperative chronic pain, had autonomic nervous system anomalies and patients with rhythm will be excluded from the study. * Intensive Care Internal Diseases Group 2 Ramsey sedation scale under 5, cooperative, with spontaneous breathing effort and extremity movement, non sinusal cardiac rhythm * Intensive Care Patients (Obese) Group 3 - patients under 40 BMI

Design outcomes

Primary

MeasureTime frameDescription
Analgesia Nociception Index for pain monitorization3 MonthsThe duration between two R waves within heart rate variations (filtering the variations in respiratory cycles). A numeric measure of parasympathetic tonus will be obtained. This variation is between (pΣ) 0 and 100.

Contacts

Primary ContactAli Sefik Koprulu, MD
sefik.koprulu@yeniyuzyil.edu.tr+905322677226
Backup ContactErsi Kalfoglou, PhD
ersi.kalfoglu@yeniyuzyil.edu.tr+905323500656

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026