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High-Intensity Interval Training and Fat Mass Losses

Effect of Two Isoenergetic Modes of High-Intensity Interval Training on Total and Abdominal Fat Mass Loss in Men With Overweight or Obesity.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05311800
Acronym
RIESLING
Enrollment
9
Registered
2022-04-05
Start date
2021-09-01
Completion date
2022-07-01
Last updated
2023-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Men, Overweight and Obesity

Keywords

cycling, running, high-intensity interval training, fat mass, visceral tissue, health

Brief summary

The aims of this study was to compare two isoenergetic HIIT (High-intensity Interval training) programs (cycling vs. running) on body composition, substrate oxidation at rest and during a moderate exercise, muscle functionality, glycaemic control, lipid profile, inflammation, maximal aerobic capacity (VO2max) and gut microbiota composition in men with overweight or obesity. The investigators hypothesized that both programs could decrease total, abdominal and visceral fat mass but due to differences in muscle solicitation, metabolism adaptation and blood flow, and that running could favors greater fat mass losses.

Detailed description

The first aim of this study was to compare two isoenergetic HIIT programs (cycling vs. running) on body composition in men with overweight or obesity. 20 men with overweight or obesity should completed HIIT program three times a week during twelve weeks. i) High intensity interval training - BIKE (HIIE BIKE) 10 cycles of speeding up for 45 s at 80-thPHR followed by pedaling slowly (40% thPHR) for 1m30s (37min30s) ii) High intensity interval training - RUN (HIIE RUN) 9 cycles of speeding up for 45 s at 80-thPHR followed by pedaling slowly (40% thPHR) for 1m30s (35min15s) Body composition will be measured before and after HIIT program by Dual-energy X-ray absorptiometry (DXA).

Interventions

OTHERPhysical activity

Comparison of HIIT mode (running vs cycling)

Sponsors

Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Masking description

Data collected on the volunteers will be made anonymous.

Intervention model description

2 groups : running vs cycling

Eligibility

Sex/Gender
MALE
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* men (18 to 65 years old) * with overweight or obesity (BMI \> 25 kg/m2 and ≤ 40 kg/m2)

Exclusion criteria

* medical contraindications to intense physical activity, * painful joints, * taking ß-blocker

Design outcomes

Primary

MeasureTime frameDescription
HIIT mode and fat mass change (g)At the first and the last training - week 1 and 12change of total fat mass (in grams from DXA analysis) after 3 months of training- HIIT mode comparison
HIIT mode and abdominal fat mass change (g)At the first and the last training - week 1 and 12change of abdominal fat mass (in grams from DXA analysis) after 3 months of training- HIIT mode comparison

Secondary

MeasureTime frameDescription
Rate of carbohydrate and lipid oxidation (g.min-1) during a sub-maximal exercise by measuring gaz exchange.At the first and the last training - week 1 and 12Carbohydrate and lipid oxidation rate (g.min-1) during a submaximal exercise before and after the HIIT protocol. HIIT mode comparison.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026