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Study of the Closed-loop Treatment Concept of Atrial Fibrillation in the Atrial Fibrillation Population

Application of the Closed-loop Treatment Concept of Atrial Fibrillation in the Atrial Fibrillation Population in the Northern Shanghai Community

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05311137
Acronym
CONTROL-AF
Enrollment
5000
Registered
2022-04-05
Start date
2022-05-01
Completion date
2032-01-01
Last updated
2022-05-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation

Keywords

atrial fibrillation;closed-loop treatment;

Brief summary

This study aims to evaluate the concept of closed-loop treatment of atrial fibrillation for the optimization of the treatment strategy.

Detailed description

This study aims to evaluate the concept of closed-loop treatment of atrial fibrillation for the optimization of the treatment strategy, the improvement of disease outcome and the economic value of the atrial fibrillation population in the northern Shanghai community. Improve the disease cognition of patients with atrial fibrillation, and promote the development of the concept of closed-loop treatment of atrial fibrillation.

Interventions

PROCEDURERadiofrequency ablation

Combined use of radiofrequency ablation, cryoablation, left bundle branch pacing, and left atrial appendage closure according to the actual situation of the patient.

Sponsors

Shanghai 10th People's Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 100 Years

Inclusion criteria

* atrial fibrillation patients;Ability to act autonomously, understand and sign informed consent;

Exclusion criteria

* none(All patients with atrial fibrillation were enrolled in this study indiscriminately and followed up)

Design outcomes

Primary

MeasureTime frameDescription
Atrial fibrillation recurrence2 yearsThe recurrence of atrial fibrillation and the degree of burden of atrial fibrillation in patients.
Heart failure5 yearsDegree of heart failure (including EF%, NYHA score, etc.)
Stroke5 yearsstroke attack(Check for new cerebral infarction by MRI)

Secondary

MeasureTime frameDescription
bleeding2 yearsmajor bleeding event
Cardiovascular MACE events5 yearsCardiovascular MACE events

Countries

China

Contacts

Primary ContactDongDong Zhao, PhD
zhaodd@tongji.edu.cn+86 18917684008
Backup ContactJun Zhang, MD
zhangjun_njmu2011@163.com+86 15000420881

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026