Intensive Care Units, Posterior Reversible Encephalopathy Syndrome
Conditions
Brief summary
The purpose of this study is to explore the predictors of ICU admission of obstetric posterior reversible encephalopathy syndrome.
Detailed description
The investigators retrospectively collected data (General information, clinical data, biochemical indicators, imaging features, and pregnancy outcome) from pregnant woman diagnosed with PRES to explore the predictors of ICU admission during 2012 to 2021.Then, the investigators grouped all the patients into ICU group and Non-ICU group according to ICU admission or not.
Interventions
OTHERWhether the patient needs to be admitted to the ICU
According to ICU admission or not, patients were grouped into ICU group and NOT-ICU group.
Sponsors
Dunjin Chen
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
16 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
1. Pregnant Women were diagnosed of PRES. 2. all patients provided written informed consent
Exclusion criteria
1. patients combined with other neurological disorders 2. patients combined with mental illness
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Blood Pressure(BP) | The BP of patients was obtained immediately at the onset of symptoms. | blood pressure including systolic blood pressure (SBP), and diastolic blood pressure (DBP). |
| severity of the edema | Cranial Imaging was examined immediately at the onset of symptoms, such as s headaches, visual changes, seizures, consciousness impairment. | The extent and severity of the edema observed in the lesion area were graded on a scale of 0-5 by evaluating FLAIR images.(0, normal; 1, limited cortical or subcortical white matter oedema; 2, white matter oedema \> cortical oedema, white matter oedema extending into deep white matter; 3, white matter oedema \> cortex oedema, oedema extending to the ventricular surface; 4, the involved regions substantially extend to the ventricular surface and are almost com- pletely confluent; 5, involved regions are fully confluent and con- tinuous, ventricular deformity due to the oedema). |
| pregnancy outcomes | The pregnancy outcomes will record immediately when the patients deliver. | The rates of stillbirth and premature birth (gestation less than 37 weeks) in PRES patients. |
| biochemical parameters | Biochemical indicators were collected within 1 week of the hospital stay. | The level of lactate dehydrogenase(LDH) will be measured，and LDH﹥380U/L means a worse outcome. |
Countries
China
Outcome results
None listed