Adjuvant Therapy, Fertility Outcomes, Fertility-sparing Surgery, Hormone Therapy, Low Grade Endometrial Stromal Sarcoma of Uterus (Diagnosis), Recurrence, Survival Outcomes
Conditions
Brief summary
This study is to investigate the survival outcomes and fertility outcomes in patients with uterine low-grade endometrial stromal sarcoma (LGESS) treated in Peking Union Medical College Hospital. All primary and recurrent LGESS patients will be enrolled. The study will collect retrospectively data consisting of epidemiological characteristics, surgical, medical treatment and adjuvant therapy. Details about recurrence, mortality, pregnancy and obstetrical outcomes are also followed as primary endpoints. Fertility-sparing procedures, including uterine-sparing and ovary-sparing surgeries will be recorded specifically.
Interventions
PROCEDURESurgical treatment with and without fertility-sparing procedures
Patients accepted surgeries for LGESS and relevant adjuvant therapy if indicated.
Sponsors
Lei Li
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Aged 18 years or older * Confirmed of LGESS * Acceptance of surgical treatment for LGESS * With detailed follow-up outcomes
Exclusion criteria
\- Not meeting all of the inclusion criteria
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Progression-free survival | One year | Progression-free survival after surgery |
| Overall survival | One year | Overall survival after surgery |
| Pregnancy rate | One year | Pregnancy rate after surgery in patients with fertility-sparing patients |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Miscarriage rate | One year | Miscarriage rate after surgery in patients with fertility-sparing patients |
| Full-term pregnancy rate | One year | Full-term pregnancy rate after surgery in patients with fertility-sparing patients |
Countries
China
Contacts
Primary ContactLei Li, M.D.
Outcome results
None listed