Appendicitis Acute, Post Operative Pain, Surgery
Conditions
Keywords
Postoperative pain, Laparoscopic appendectomy, Transversus abdominis plane block, Quadratus Lumborum Block, Local anesthetic
Brief summary
Laparoscopic appendectomy causes postoperative pain. The primary objective of this prospective randomized controlled study is to compare the effect of ultrasound (US)-guided quadratus lumborum block (QLB) on 24-hour cumulative opioid requirements with transversus abdominis plane (TAP) block.
Detailed description
168 patients (ASA I-II-III) between 18 and 65 years of age, who were to undergo laparoscopic appendectomy, were randomized and divided into two groups. 32 patients were dropout for different reasons.(68 patients in each of the TAP block and QLB block groups). TAP block was performed for TAP group and QLB block was performed for QLB group. Postoperative analgesia was provided by intravenous tramadol hydrochloride using a patient-controlled analgesia device. 24-hour total tramadol hydrochloride consumption was primary outcome measure.Postoperative numeric rating scale values were the secondary outcome measure.
Interventions
PROCEDURETransversus abdominis plane block
The investigators performed transversus abdominis plane block to that patient group for postoperative analgesia
PROCEDUREQuadratus Lumborum Block
The investigators performed quadratus lumborum block to that patient group for postoperative analgesia
Sponsors
Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Ages of 18-65 * Patients who will undergo laparoscopic appendectomy * ASA I-II-III patients
Exclusion criteria
* Clinically known local anesthetic allergy * Morbid obesity (body mass index\>40 kg m2) * Clinically diagnosis of opioid, alcohol and substance dependence * Clinically diagnosis of psychiatric disease * Coagulopathy * Patients with ASA IV-V
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative 24-hours total tramadol hydrochloride consumption | 24 hours postoperatively | This will be measured by pca device in the 24 hour after |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Numerical rating scale (NRS) scores of patients | 24 hours postoperatively | Numerical rating scale (NRS) at 1, 6, 12, 18, 24th hours. A numerical rating scale (NRS) requires the patient to rate their pain on a defined scale. For example, 0-10 where 0 is no pain and 10 is the worst pain imaginable. |
Countries
Turkey (Türkiye)
Outcome results
None listed