Paroxysmal Positional Vertigo & Repositioning Maneuvers

Effect of Modified Epley's & Semont's Maneuvers With or Without Beta-histine on Benign Paroxysmal Positional Vertigo: A Randomized Control Trail

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05309538

Enrollment

Registered

2022-04-04

Start date

2021-01-02

Completion date

2022-01-01

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign Paroxysmal Positional Vertigo

Keywords

BPPV

Brief summary

: Benign Paroxysmal Positional Vertigo is a condition related to vestibular system accompanied by dizziness, tinnitus and balance problems leading to increased fall risk and potential disability. Various treatment options are available including pharmacotherapy and vestibular rehabilitation with varied results

Detailed description

Objective: The objective of this study was to compare the efficacy of Modified Epley & Semont's maneuver with and without Betahistine for BPPV Material & Methods: The study was a single blind randomized control trail. Total number of patients were 97 as calculated by Epitool calculator. Duration of the study was of one year from 2 January 2021 to 1st January 2022. Out of a total 97 patients, 90 met the inclusion criteria. These participants were randomized by lottery method into two equal groups. Group A (control group) was receiving both maneuvers only while group B (experimental group) included participants receiving betahistine along with both maneuvers. The impact of dizziness and quality of life was measured through EQ-5D-5L questionnaire and dizziness handicap inventory (DHI) in order to analyze the effectiveness of treatments. Pre and Post treatment results were compared within group by Wilcoxon rank test and for between groups, Mann Whitney U test was performed

Interventions

OTHERModified eply & Semont maneuver

repositioning maneauvers

OTHERbetahistine & Modified eply & Semont maneuver

antihistamine plus repositioning maneuvers

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Intervention model description

2 groups , group A contro group and group B experimental group

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* age between 18-60 * positive modified Dix Hil pike test * repetitive vertigo spells affecting activities of daily livings (ADLs)

Exclusion criteria

* any cervical spine problem * vertigo due to central disease * tumors * systemic disease * cardiac disease * Parkinson disease * bed bound patients

Design outcomes

Primary

Measure	Time frame	Description
DHI	1 month	dizziness handicap inventery
EQ-5D-5L	1 month	quality of life

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 12, 2026