Aging
Conditions
Brief summary
This study is to investigate the improveing effects of the Crassocephalum rebens extract on skin conditions in normal people.
Interventions
DIETARY_SUPPLEMENTCrassocephalum rabens extract
dosage: a capsule (180 mg)/day; duration: 1 month
Sponsors
Chia Nan University of Pharmacy ＆ Science
Greenyn Biotechnology Co., Ltd.
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. Age over 20 years 2. Healthy people
Exclusion criteria
1. Non-volunteer 2. Pregnant and lactating women 3. Hypersensitivity to the assigned product 4. Diagnosed with skin diseases, liver diseases, kinedy disease, and other severe diseases 5. Cosmetic, drug, or food allergies 6. Concurrent aesthetic treatments (e.g., intense pulse light, medical peelings, or laser therapy) 7. Aceepted aesthetic treatments one month ago before the study 8. Chronic sun exposure (over 3 hours/day) 9. The members of the research team
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Measurement of skin hydration | Week 0 | Corneometer CM825 is used to measure the moisture of upper cheek (unit: Corneometer® unit) |
| Measurement of skin brightness | Week 0 | Chroma Meter MM500 is employed to measure the brightness of upper cheek (unit: L\* value (L\* range: 0-100)). |
| Measurement of skin texture | Week 0 | Visia® skin analysis system is used to measure the skin texture of full face (unit: number of fine lines) |
| Measurement of skin spots | Week 0 | Visia® skin analysis system is used to measure the skin spots of full face (unit: number of spots) |
| Measurement of collagen content | Week 0 | DermaLab® Series SkinLab Combo (Cortex) is employed to measure skin collagen content of upper cheek (unit: collagen density) |
| Measurement of Crow's feet | Week 0 | Visia® skin analysis system is used to measure the skin spots of full face (unit: number of Visia® skin analysis system is used to measure the skin spots of full face (unit: number of fine lines around eyes) |
| Measurement of skin elasticity | Week 0 | Cutometer® is used to measure the skin elasticity of upper cheek (unit: mm) |
| Measurement of skin wrinkles | Week 0 | Visia® skin analysis system is used to measure the skin wrinkles of full face (unit: number of wrinkles) |
| Measurement of skin pores | Week 0 | Visia® skin analysis system is used to measure the skin spots of full face (unit: number of pores) |
Countries
Taiwan
Outcome results
None listed