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Postoperative Kidney Functions in Geriatric Major Gynecologic-Oncologic Surgery

Evaluation of Postoperative Kidney Functions in Geriatric Patients Undergoing Major Gynecologic-Oncologic Surgery: A Retroceptive - Cohort Study

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05308810
Enrollment
150
Registered
2022-04-04
Start date
2022-04-30
Completion date
2022-07-31
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Renal Injury, Geriatrics, Gynecologic Surgery

Keywords

Geriatrics, Acute Renal Injury, Gynecologic Surgery

Brief summary

The increasing number of patients who develop perioperative acute kidney injury (AKI) is partly related to the aging population and the increasing number of individuals with chronic comorbidities, particularly those with premorbid chronic kidney disease. Anesthesiologists and surgeons will increasingly have to deal with such patients who are elderly and have comorbidities and require major surgery. The aim of this study was to determine the incidence of postoperative acute kidney injury (primary aim) in patients aged 65 and over who underwent elective major gynecological-oncological surgery under general anesthesia in Ankara City Hospital Gynecology-Oncology Operating Room between January 2020-2022 and were followed up in the PACU in the postoperative period. To investigate risk factors and their results in a retrospective manner in line with the KDIGO criteria (secondary purpose).

Interventions

PROCEDUREMajor Gynecologic- oncologic Surgery

Major Gynecologic-Oncologic surgery between january 2020 - january 2022

Sponsors

Ankara City Hospital Bilkent
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
65 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

* patients underwent major abdominal gynecologic oncologic surgery between January 2021 and January 2022 * followed in the PACU

Exclusion criteria

* Patients with inaccessible data and missing data

Design outcomes

Primary

MeasureTime frameDescription
the incidence of the patients with AKI STAGE 148 hours after surgeryAKI STAGE 1 : increase Cr ≥ 0.3 mg/dl or increase Cr to 1.5-1.9 times from baseline; or urine volume \< 0.5 ml/kg/h for 6-12 hours AKI STAGE 2 : increase to 2-2.9 times from baseline; or urine volume \< 0.5 ml/kg/h for ≥ 12 hours AKI STAGE 3 : increase Cr to ≥ 3 times from baseline; or increase Cr ≥ 4 mg/dl or initiation of renal replacement therapy or decrease in GFR to \<35mL/min/1.73 m2 or urine volume \< 0.3 ml/kg/h for ≥ 24 hours or Anuria for ≥ 12 hours
the incidence of the patients with AKI stage 248 hours after surgeryAKI STAGE 1 : increase Cr ≥ 0.3 mg/dl or increase Cr to 1.5-1.9 times from baseline; or urine volume \< 0.5 ml/kg/h for 6-12 hours AKI STAGE 2 : increase to 2-2.9 times from baseline; or urine volume \< 0.5 ml/kg/h for ≥ 12 hours AKI STAGE 3 : increase Cr to ≥ 3 times from baseline; or increase Cr ≥ 4 mg/dl or initiation of renal replacement therapy or decrease in GFR to \<35mL/min/1.73 m2 or urine volume \< 0.3 ml/kg/h for ≥ 24 hours or Anuria for ≥ 12 hours
the incidence of the patients with AKI stage 348 hours after surgeryAKI STAGE 1 : increase Cr ≥ 0.3 mg/dl or increase Cr to 1.5-1.9 times from baseline; or urine volume \< 0.5 ml/kg/h for 6-12 hours AKI STAGE 2 : increase to 2-2.9 times from baseline; or urine volume \< 0.5 ml/kg/h for ≥ 12 hours AKI STAGE 3 : increase Cr to ≥ 3 times from baseline; or increase Cr ≥ 4 mg/dl or initiation of renal replacement therapy or decrease in GFR to \<35mL/min/1.73 m2 or urine volume \< 0.3 ml/kg/h for ≥ 24 hours or Anuria for ≥ 12 hours

Countries

Turkey (Türkiye)

Contacts

Primary ContactAysun Postacı
aysunposta@yahoo.com+905323520383
Backup ContactNamık Özcan
+9005324914531

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026