COVID-19 Respiratory Infection, Physical Therapists, Rehabilitation
Conditions
Keywords
covid-19, training program, respiratory physiotherapy
Brief summary
The purpose of this study is to investigate the effects of a training program in patients that have suffered a COVID infection
Detailed description
Once patients have been selected and meet inclusion criteria, they will sign informed consent. They will make a first visit to obtain the basal parameters. Once done, they will start the individualized training program for 12 weeks 3 times a week.
Interventions
OTHERInterval training + analytical strength
Patients will receive a training program
OTHERInterval training + analytical strength and IMT
Patients will receive a training program + IMT
Sponsors
Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Men and women ≥18 years * Patients discharged from the Pulmonology Service with a diagnosis of COVID-19 by positive PCR and with severe pneumonia. * At least three months after the presence of at least one of the following criteria: 1. MRC dyspnea greater than or equal to 2. 2. Decrease in the meters walked with respect to the reference values in the 6-minute walking test. C) Decreased respiratory muscle strength measured at Maximum Inspiratory Pressure (PIM) and / or Maximum Expiratory Pressure (PEM) with respect to reference values. * Sign informed consent from the study
Exclusion criteria
* Patients who do not want to be included in the study. * Pregnant women. * Impossibility to perform ergometry or ultrasound.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| changes in walking distance in the 6 minutes walk test | Baseline and 12 weeks after | 6MWT is a submaximal test performed in 30 meters corridor. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| changes in the maximum watts generated | Baseline and 12 weeks after | Cardiopulmonary exercise test will be performed as maximal test |
| changes in (oxygen consumption) VO2 max | Baseline and 12 weeks after | Cardiopulmonary exercise test will be performed as maximal test |
| changes in peak VO2 | Baseline and 12 weeks after | Cardiopulmonary exercise test will be performed as maximal test |
| changes in the diaphragmatic path | Baseline and 12 weeks after | Diaphragm echocardiography will be performed |
| changes in diaphragm thickness | Baseline and 12 weeks after | Diaphragm echocardiography will be performed |
| changes in diaphragmatic shortening | Baseline and 12 weeks after | Diaphragm echocardiography will be performed |
| changes in dyspnea | Baseline and 12 weeks after | Measured with mMRC scale (scores from 0-4) |
Countries
Spain
Outcome results
None listed