Antibody, Cord, Maternal, Vaccine
Conditions
Keywords
Covid-19, antibody, pregnancy
Brief summary
This is a prospective clinical study aiming to investigate on the transplacental antibody transmission post Covid-19 infection during pregnancy.
Detailed description
Covid -19 infection has been a significant public health burden as it shifted the paradigm of infectious diseases aiming to control the spread and enhance public immune protection. The introduction of Covid -19 vaccination in December 2020 aimed to combat the infection, thus tremendously helping to flatten the disease worldwide. Channeling the vaccine for the obstetrics field is one of the hallmark strategies to reduce maternal morbidity and mortality. The efficacy of vaccination for the pregnant lady has been established. However, fetus protection via transmission of the antibody during pregnancy is still uncertain. Therefore, this study aims to consolidate further evidence of transplacental antibody post-maternal vaccination aiming for fetal protection following delivery.
Interventions
None listed
Sponsors
Malaysia Automotive Robotics and Innovation of Technology Institute
National University of Malaysia
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* term pregnancies at 37 weeks or more * vaccinated 2 doses * in labour
Exclusion criteria
* unvaccinated * preterm labour less than 37 weeks * multiple pregnancies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Maternal to Neonatal Transmission Antibody Covid-19 Study - The TRAB CoV-19 | 30 minutes after delivery | Quantification of Covid-19 antibody levels in maternal and cord blood samples |
Countries
Malaysia
Outcome results
None listed