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Effective Volemia in Older Adults With Orthostatic Hypotension

Effective Volemia in Older Adults With Orthostatic Hypotension, Feasibility Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05304806
Acronym
EVO
Enrollment
20
Registered
2022-03-31
Start date
2022-04-20
Completion date
2022-10-21
Last updated
2024-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthostatic Hypotension

Keywords

older, orthostatic hypotension, volemia, clinical sonography

Brief summary

Clinical and biological assessments of volemia are challenging in older patients as they are more likely to present non-typical signs. Point of care ultrasonography (POCUS) using heart and lung exploration is a relevant tool to assess volemia in adults with little data in older adults. The primary objective of the study is to evaluate feasibility of positional POCUS in aging patients. The secondary objectives are to assess the variability of measurements between decubitus and sitting position.

Detailed description

This is a monocentric study. Twenty patients will be enrolled, aged of 70 years and older. POCUS parameters, duration of procedure and measurements will be recorded for each patients.

Interventions

None listed

Sponsors

Assistance Publique - Hôpitaux de Paris
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
70 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* 70 years and older * Orthostatic hypotension or venous insufficiency * Affiliated to a social security or beneficiary

Exclusion criteria

* Refusal to participation to the study * Cognitive disorder * Unable to keep sitting posture for up to 30 minutes * Foreign patients under french AME scheme

Design outcomes

Primary

MeasureTime frameDescription
Duration of recording during positional echography3 monthsFeasibility of positional echography assessed by \- Duration of recording (minutes)
Feasibility of positional echography3 monthsFeasibility of positional echography assessed by \- Number of good quality imaging (out of 5 pre specified views : parasternal long axis view, parasternal short axis view, apical views 4 and 5 chamber, subxiphoid view, inferior vena cava view)

Secondary

MeasureTime frameDescription
Cardiac ultra sound parameters: E and A waves velocity3 months\- E and A waves velocity (cm/sec) (mitral Doppler)
Cardiac ultra sound parameters: left ventricle diastolic diameter3 months\- Left ventricle diastolic diameter mm/m2
Cardiac ultra sound parameters: left atrial size3 months\- Left atrial size (cm2)
Cardiac ultra sound parameters: Inferior vena cava size and compliance3 months\- Inferior vena cava size (mm) and compliance (%)
Cardiac ultra sound parameters: left ventricle ejection fraction3 months\- Left ventricle ejection fraction (%)

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026