Combination of Spinal-Epidural With General Anesthesia in Patients Undergoing Mega-Liposuction Surgery

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05301127

Enrollment

Registered

2022-03-29

Start date

2022-01-11

Completion date

2024-10-01

Last updated

2024-10-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Combination of General Anesthesia to Spinal and Epidural Techniques

Brief summary

The combination of general anesthesia to spinal and epidural techniques (CSEGA) proved to have a synergistic effect, thus, the use of sub-anesthetic doses can provide satisfactory anesthetic and analgesic results. CSEGA has several known advantages including appropriate postoperative analgesia, shows some benefit in the intraoperative blood loss control causing a decreased need for blood transfusion, rapid regain of the gastrointestinal actions and decreases the incidence of postoperative respiratory complications. Unfortunately, the drawbacks of using neuro-axial anesthesia in combination to general anesthesia will be not thoroughly introduced in many researches, thus, remain unclear.

Interventions

DEVICEspinal-epidural device

received combined spinal-epidural-general anesthesia.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

1. Inclusion criteria: * Patients aged from 18 to50 years. * ASA I-II. * undergoing elective liposuction surgery * BMI from 25 to 40 kg/m2 2.

Exclusion criteria

* Patient refusal * ASA III-IV. * Patients aged less than 18 or more than 50. * Body mass index \>40. * Any contraindications to neuro-axial block such as coagulopathy or spine deformity * Chronic opioid consumption, * History of parenteral or oral analgesic intake within the last 48hours.

Design outcomes

Primary

Measure	Time frame	Description
morphine consumption	24 hours	postoperative morphine consumption

Secondary

Measure	Time frame	Description
Postoperative patient satisfaction	24 hours	1 = very unsatisfactory; 2 = unsatisfactory; 3 = indifferent; 4 = satisfactory; and 5 = very satisfactory.
Intraoperative surgeon satisfaction.	6 hours	using 1-4 scales (1, bad; 2, moderate; 3, good; 4, excellent;
Incidence of complications	24 hours	such as hypotension, bradycardia, nausea and vomiting, postoperative shivering,
Blood loss	6 hours	intraoperative Blood loss

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026