HPV Integration
Conditions
Brief summary
The stratified analysis by the level of HPV DNA integration in HSIL and cervical cancer will be drawn to explore whether the status of HPV integration makes any difference in the progression of cervical cancer. The purpose of the research is to reduce the miss of cervix lesions and prove that HPV integration detection is sensitive in cervical cancer precise screening.
Interventions
DIAGNOSTIC_TESTHPV integration test
The stratified analysis by the level of HPV DNA integration in HSIL and cervical cancer will be drawn to explore whether the status of HPV integration makes any difference in the progression of cervical cancer. The purpose of the research is to reduce the miss of cervix lesions and prove that HPV integration detection is sensitive in cervical cancer precise screening.
Sponsors
Tongji Hospital
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* HPV-positive patients； Patients have completed HPV detection, TCT, and HPV integration detection before surgery or biopsy； Patients with priced diagnoses accepted treatment according to ASCCP Risk-Based Management Consensus Guidelines for Abnormal Cervical Cancer Screening Tests and Cancer Precursors； Patients who are voluntary participants in this research and cooperate to follow-up with subscribing informed consent.
Exclusion criteria
* Patients who are not suitable for the trial； Patients existing other subtype malignancy tumors are still in treatment.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Tissue pathological diagnosis | 1year since HPV integrated test | Tissue pathological diagnosis in 1 year since HPV integrated test |
Countries
China
Contacts
Primary ContactShuang Li, PHD
Outcome results
None listed