Multiple Sclerosis, 3D Gait Analysis, Vestibular Rehabilitation
Conditions
Keywords
gait analysis, multiple sclerosis, vestibular, kinetic, kinematic
Brief summary
In the literature, the results of vestibular rehabilitation treatment applied in patients with Multiple Sclerosis (MS) have been investigated in detail under the headings such as fatigue, physical activity level, and quality of life, and its effects on walking have also been tried to be examined. However, in the studies conducted, gait assessments were made through questionnaires and timed tests, and devices that provide more objective data such as 3-dimensional gait analysis were not used. Again, the effects of vestibular rehabilitation programs on dual-task were not examined in previous studies. Therefore, the aims of our study are: 1. To determine the effect of individually designed vestibular rehabilitation exercises on the kinetic and kinematic components of walking; 2. To determine the effect of vestibular rehabilitation exercises specially designed for the person on gait parameters during cognitive and motor tasks.
Interventions
OTHERVestibular exercises
The vestibular exercise program basically consists of 3 groups of exercises: adaptation, substitution, and habituation exercises. It is aimed to provide vestibular adaptation with adaptation exercises. Exercises that include visual and somatosensory cues to improve gaze and postural stability constitute substitution exercises. Balance exercises can be performed with eyes open and closed, or somatosensory cues can be changed by performing them on soft ground. Removing or reducing clues allows the patient to use other systems as well. The basis of habituation exercises is the reduction of the pathological response as a result of repeated exposure to the provocative stimulus. Habituation is specific to the type, intensity, and direction of stimuli. In most cases, the movement that stimulates the pathological response is less frequently performed during daily activities and promotes compensation for the initially abnormal signal of treatment.
OTHERStandard neurorehabilitation exercises
A neurorehabilitation program based on stretching, strengthening, posture, mobilization, static and dynamic balance exercises (standing on one leg, tandem, balance board, etc.) will be applied.
Sponsors
Istanbul University - Cerrahpasa
Istanbul Kültür University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
25 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Between aged 25-60 years * Diagnosed with MS for at least 5 years * Relapsing and progressive MS according to Mc Donald criteria * EDSS score of ≤ 3.5 ≤ 6 * Modified Ashworth Scale \< 3 * Being eligible to work by a neurologist
Exclusion criteria
* Having had an MS-related attack in the 3 months before the study * Changes in medications within 6 months prior to the study * To have participated in the rehabilitation program within 1 month before the study * Serious neurological, cardiac, pulmonary, rheumatological, audiovisual, or orthopedic disorders that limit assessments and/or intervention programs
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 3D Gait Analysis System - pre assesment | It will be done at the beginning of the study. An analysis session lasts nearly 2 hours per patient. Evaluation of all participants will take approximately 2 months. | Kinetic and kinematic data of gait will be collected in the motion analysis laboratory using 6 infrared digital cameras (Vantage 5.0), 2 synchronized video cameras (Vicon Vue) and 2 force platforms (AMTI). |
| 3D Gait Analysis System - post assesment | It will be done at the end of the study. An analysis session lasting nearly 2 hours per patient. Evaluation of all participants will take approximately 2 months. | Kinetic and kinematic data of gait will be collected in the motion analysis laboratory using |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Dizziness Handicap Inventory - pre assessment | It will be done at the beginning of the study. The test lasts nearly 15 minutes. | The Dizziness Disability Inventory consists of 25 items that determine the aggravating factors of patients' dizziness and balance disorder, as well as emotional and functional outcomes in vestibular system diseases. It includes 9 items that determine emotional and functional status, and seven items that determine physical function. |
| Dizziness Handicap Inventory - post assessment | It will be done at the end of the study. The test lasts nearly 15 minutes. | The Dizziness Disability Inventory consists of 25 items that determine the aggravating factors of patients' dizziness and balance disorder, as well as emotional and functional outcomes in vestibular system diseases. It includes 9 items that determine emotional and functional status, and seven items that determine physical function. |
| One Leg Standing Test - pre assesment | It will be done at the beginning of the study. The test lasts nearly 5 minutes. | It will be used to determine the patient's standing balance. The duration of standing on one leg will be recorded with a stopwatch and 3 repetitions will be taken and the most successful score will be used in the analysis. |
| 2 Minute Walking Test - post assessment | It will be done at the end of the study. The test lasts nearly 5 minutes. | The distance that patients will walk for 2 minutes will be measured and recorded. |
| 2 Minute Walking Test - pre assessment | It will be done at the beginning of the study. The test lasts nearly 5 minutes. | The distance that patients will walk for 2 minutes will be measured and recorded. |
| One Leg Standing Test - post assessment | It will be done at the end of the study. The test lasts nearly 5 minutes. | It will be used to determine the patient's standing balance. The duration of standing on one leg will be recorded with a stopwatch and 3 repetitions will be taken and the most successful score will be used in the analysis. |
Countries
Turkey (Türkiye)
Outcome results
None listed