Stress Reaction
Conditions
Brief summary
Transcranial infrared laser stimulation is a non-invasive neuromodulation technique. The study will examine the effect of transcranial infrared laser stimulation on cardiovascular and metabolic responses to stress.
Detailed description
Physiological responses to stress may be a potential pathway by which psychological stress relates to cardiovascular disease. Disproportionate (metabolically exaggerated) stressor-evoked cardiovascular reactions may accelerate atherosclerosis or influence risk of greater cardiovascular disease endpoints. The aim of this project is to use an experimental approach to examine if neuromodulation (transcranial infrared laser stimulation) alters stressor-evoked metabolic and cardiovascular responses.
Interventions
Sham Comparator: Participants will receive 8 counts of 60 seconds of the same laser to the right forehead, however the laser power will be turned off and will be 0 Watts. Transcranial infrared laser stimulation: Participants will receive 8 counts of 60 seconds of transcranial infrared laser stimulation to the right forehead. The wavelength will be 1064 nm and the laser power will be 3.4 Watts.
Sponsors
Baylor University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
18-30 years old
Exclusion criteria
History of a diagnosed chronic medical or neurological disorder Current pregnancy Current illness or infection (e.g., cold, flu) Any condition that would prohibit them from engaging in physical exercise
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Oxygen consumption in response to acute psychological stress | Immediately following intervention (up to 60 minutes) | This measurement takes into account oxygen consumption at baseline and during the stress task. |
| Heart rate in response to acute psychological stress | Immediately following intervention (up to 60 minutes) | This measurement takes into account heart rate at baseline and during the stress task. |
| Additional heart rate in response to acute psychological stress | Immediately following intervention (up to 60 minutes) | This measurement takes into account additional heart rate at baseline and during stress. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Perceived stress | Immediately following intervention (up to 60 minutes) | Ratings of perceived stressfulness (1 = not at all stressful, 7 = very stressful) of the acute psychological stress task |
Countries
United States
Outcome results
None listed