Acute Heart Failure (AHF), Chronic Heart Failure, Heart Failure
Conditions
Keywords
Decompensated, Outpatient, Treatment, Hospitalization, Mortality, Heart Failure, Americas, Registry, Inpatient
Brief summary
The purpose of this study is to better characterize and understand the population of patients with ambulatory or acutely decompensated heart failure in the American continent, getting to know their sociodemographic, clinical and paraclinical characteristics
Detailed description
An observational, prospective and multicenter study in which ambulatory patients with a confirmed diagnosis of heart failure and those admitted to the hospitalization service due to an episode of acutely decompensated heart failure will be invited to participate in order to better characterize this population Participants who meet the eligibility criteria will be evaluated at the moment of recruitment. Follow-ups will be performed at 1, 6 and 12 months after the initial registry for hospitalized patients. For ambulatory patients follow-up will only be performed at 12 months. These initial evaluations and subsequents follow-ups will be carried out using a standardized form for the collection of hospital and outpatient data through an electronic platform The purpose of this study is to know sociodemographic, clinical (clinical presentation, hemodynamic profiles, in-hospital and outpatient management, re-hospitalization rate, proportion of mortality, cumulative survival and heart failure readmission-free survival) and paraclinical characteristics of this population
Interventions
None listed
Sponsors
Sociedad Interamericana de Cardiología (SIAC)
Consejo Interamericano de Falla Cardíaca e Hipertensión Pulmonar (CIFACAH)
Fundacion Clinica Valle del Lili
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient aged 18 years or older and one of the following: * Hospitalized patient with admission diagnosis of acutely decompensated heart failure or * Outpatient with confirmed diagnosis (main or complementary) of heart failure
Exclusion criteria
* Hospitalized patient with principal diagnosis of another cardiovascular / non-cardiovascular pathology and who develops an acute decompensation of heart failure during hospitalization. * Patient on heart transplant waiting list * Patient who has implanted or is in process of implanting a long-term ventricular assist device (eg, Heart Mate II, Heart Mate III) as a target therapy or bridge therapy to other therapies * Patient in whom palliative management has been previously defined for his/her cardiac condition (i.e. Heart failure) or for another associated medical condition (cancer, chronic obstructive pulmonary disease (COPD), etc.) * Patient who is discharged or referred to another institution within 48 hours of hospital stay * Inability to comply with programmed follow-ups (telephone or in person) due to social, personal or other conditions considered by the principal investigator * Life expectancy less than 6 months given a condition other than heart failure (Cancer, COPD, etc.)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Characteristics of population with diagnosis of heart failure in America | Baseline | Sociodemographic characteristics of patients with heart failure |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Relation between outpatient treatment of heart failure with proportion of hospitalization and mortality | Baseline and at Month 12 | Relate outpatient pharmacological treatment with the proportion of hospitalization and mortality |
| Clinical and hemodynamic presentation of acutely decompensated heart failure | Baseline | Describe the clinical and hemodynamic presentation of patients with acute decompensated heart failure |
| In-hospital management of acutely decompensated heart failure | Baseline | Describe the in-hospital management of patients with acutely decompensated heart failure |
| Proportion of in-hospital mortality related with acute decompensation of heart failure | Baseline | Determine the proportion of in-hospital mortality related with acute decompensation of heart failure |
| Proportion of rehospitalization at 1, 6, 12 months after hospital discharge | Month 1, Month 6 and Month 12 | Determine the proportion of rehospitalization at 1, 6 and 12 months after hospital discharge |
| Proportion of mortality at 1, 6, 12 months after hospital discharge | Month 1, Month 6 and Month 12 | Determine the proportion of mortality at 1, 6 and 12 months after hospital discharge |
| Relation between hemodynamic profile of decompensation with proportion of mortality at 1, 6, 12 months after hospital discharge | Baseline, Month 1, Month 6 and Month 12 | Relate the hemodynamic profile of decompensation with the proportion of in-hospital and ambulatory mortality at 1, 6 and 12 months after hospital discharge. |
| Outpatient management of heart failure | Baseline and at Month 12 | Describe the ambulatory/outpatient management of patients with heart failure |
| Relation between in-hospital pharmacological treatment with proportion of readmissions at 1, 6, 12 months after hospital discharge | Month 1, Month 6 and Month 12 | Relate hospital pharmacological treatment with the proportion of readmissions at 1, 6 and 12 months after hospital discharge. |
| Relation between outpatient pharmacological treatment with proportion of hospitalization and mortality at 1, 6, 12 months after hospital discharge | Month 1, Month 6 and Month 12 | Relate outpatient pharmacological treatment with the proportion of hospitalization and mortality at 1, 6 and 12 months after hospital discharge. |
| Differences among heart failure treatment considering sociodemographic characteristics | Baseline | Describe the differences among inpatient and outpatient treatment taking into account different demographic characteristics such as: gender, age, comorbidities, among others |
| Differences among proportion of rehospitalization and heart failure mortality considering sociodemographic characteristics | Baseline | Describe the differences in the proportion of rehospitalization, hospital and outpatient mortality, taking into account different demographic characteristics: gender, age, comorbidities, among others |
| Differences among proportion of rehospitalization and heart failure mortality considering implementation of optimal medical treatment | Baseline, Month 1, Month 6 and Month 12 | Describe the differences in the proportion of rehospitalization, hospital and outpatient mortality, taking into account the implementation of optimal or recommended medical treatment in national and international guidelines |
| Differences among hospitalization and heart failure mortality considering the use of cardiac devices | Baseline, Month 1, Month 6 and Month 12 | Describe the differences between hospitalization and outpatient mortality taking into account the use of cardiac devices (cardiac resynchronization and/or implantable cardiac defibrillator) recommended in international guidelines |
| Cumulative heart failure survival and readmission-free survival | Baseline, Month 1, Month 6 and Month 12 | Evaluate cumulative survival and heart failure readmission-free survival |
| Relation between in-hospital pharmacological treatment with mortality at 1, 6, 12 months after hospital discharge | Month 1, Month 6 and Month 12 | Relate hospital pharmacological treatment with inpatient and outpatient mortality at 1, 6 and 12 months after hospital discharge. |
Countries
Argentina, Bolivia, Chile, Colombia, Costa Rica, Cuba, Dominican Republic, Ecuador, El Salvador, Guatemala, Honduras, Jamaica, Mexico, Nicaragua, Panama, Paraguay, Peru, Suriname, United States, Uruguay, Venezuela
Outcome results
None listed