Aggressive Periodontitis
Conditions
Brief summary
The current study was performed to study levels of Il-17 and Il-18 in aggressive periodontitis patients before and after non surgical periodontal therapy
Detailed description
Background:host defense factors are involved in pathogenesis of chronic periodontitis so, the current study is assessing levels of Il-17 and Il-18 in chronic periodontitis patients versus periodontally healthy controls. Subjects and methods: Fifty subjects were included; twenty five of them are diagnosed with chronic periodontitis patients and twenty five are periodontally healthy subjects. Probing depth (PD), clinical attachment level (CAL), plaque index (PI) and gingival index (GI) were recorded for all the enrolled subjects. GCF levels of Il-17 and IL-18 were analyzed by enzyme-linked immunosorbent assay (ELISA).
Interventions
PROCEDUREnon surgical periodontal therapy
Scaling and root planing
Sponsors
Future University in Egypt
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
30 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Medically free subjects . * both genders . * age range between 30 to 60 years old .
Exclusion criteria
* Subjects with periodontal surgeries in the last 6 months. * Subjects with prior use of antibiotics in the last 6 months. * Smokers. * Pregnant and lactating females were excluded. * Lactating females.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| measure levels of Il-17 and Il-18 in chronic periodontitis patients | Change from Baseline Il-17 andIl-18 at 3 months | measure levels of Il-17 and Il-18 in GCF of chronic periodontitis patients |
Countries
Egypt
Outcome results
None listed