Skip to content

Abdominal Weight Training Assisted by Cough Assist Machine on Lung Function

Effect of Abdominal Weight Training Assisted by Cough Assist Machine on Lung Function in the Patients With Prolonged Mechanical Ventilation

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05295381
Enrollment
40
Registered
2022-03-25
Start date
2019-08-21
Completion date
2020-08-13
Last updated
2022-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PMV

Keywords

prolonged mechanical ventilation, weaning ventilator, abdominal weight training, cough machine

Brief summary

The patients with prolonged mechanical ventilation (PMV) have the risk of ineffective coughing and infection due to diaphragm weakness, making it more difficult to wean. This study aimed to explore the intervention of abdominal weight training (AWT) with/ without cough machine (CM) on lung function, respiratory muscle strength and cough ability in these patients.

Detailed description

Methods 40 patients with PMV were randomly assigned to three groups: AWT group (n=12), AWT+CM group (n=14) and control group (n=14). The effectiveness on pulmonary function, respiratory muscle strength and cough ability were compared among these three groups.

Interventions

DEVICEcough machine (CM)

Cough machine training is based on the cough assist machine Comfort Cough II (CC20), in which the inhalation and exhalation times are adjusted to 1-3 seconds, and the positive and negative pressure of the lower pressure 10-15 cmH2O is gradually increased to 30-40 cmH2O for the first time, 4-6 cycles/time, repeated 4-6 times, twice a day, five days a week, until the subject is weaned off the ventilator or transferred out of the ward. A modified Borg scale was used as an indicator of perceived dyspnea.

abdominal weight exercise training (sandbag) is maintained for 30 minutes; the starting weight is 1kg to 2kg, and the previous day's weight is maintained each day as well as adding 0.5kg daily.

Sponsors

Liu Shih Feng
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

AWT group (n=12), AWT+CM group (n=14) control group (n=14).

Eligibility

Sex/Gender
ALL
Age
57 Years to 84 Years
Healthy volunteers
No

Inclusion criteria

* (1) Invasive ventilator users, * (2) Hemodynamically stable, * (3) Intubated endotracheal tube or tracheotomy tube, * (4) Clearly conscious and cooperative, * (5) Vital capacity (VC) \<10ml/kg

Exclusion criteria

* (1) Unconscious or unwilling to sign the informed consent form, * (2) No spontaneous breathing, * (3) Active bleeding with unstable hemodynamics, * (4) Acute infection symptoms, * (5) Abdominal distension, digestion problems (including nausea and vomiting), * (6) Severe heart failure (ejection fraction ≤ 30%), * (7) Unhealed wounds in the chest and abdomen, * (8) Bullous emphysema, * (9) Sensitive pneumothorax or mediastinal pneumothorax, * (10) Recent history of traumatic stress, * (11) Acute head and neck injury (unless the injury site is immobilized)

Design outcomes

Primary

MeasureTime frameDescription
Maximum inspiratory pressure change by the interventionChange between 1 day before and 2 weeks after the interventionlung function
Maximum expiratory pressure change by the interventionChange between 1 day before and 2 weeks after the interventionlung function

Secondary

MeasureTime frameDescription
vital capacity change by the interventionChange between 1 day before and 2 weeks after the interventionlung function

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026