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Beetroot Extract and Its Influence on Cardiovascular and Autonomic Recovery From the Effort in Healthy Males

Beetroot Extract and Its Influence on Cardiovascular and Autonomic Recovery From the Effort in Healthy Males

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05294198
Enrollment
16
Registered
2022-03-24
Start date
2021-05-10
Completion date
2021-11-12
Last updated
2022-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Males

Brief summary

There is no evidence that beetroot extract (Beta vulgaris L.) is advantageous for the recovery of cardiovascular parameters and the autonomic nervous system (ANS) after submaximal aerobic exercise. The objective of this study is to evaluate the effect of beetroot extract supplementation on the recovery of cardiorespiratory and autonomic parameters after a submaximal aerobic exercise session. Healthy male adults will perform a cross-over, randomized, double-blind, and placebo-controlled trial. Beetroot extract (600mg) or placebo (600mg) will be ingested 90 minutes before evaluation in randomized days. Systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse pressure (PP), mean arterial pressure (MAP), heart rate (HR), and HR variability (HRV) indexes will be recorded at Rest and during 60 minutes of recovery from exercise.

Interventions

DIETARY_SUPPLEMENTBeetroot extract

Beetroot extract capsule

Sponsors

University of Pernambuco
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
MALE
Age
18 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy males; * Physically active according to International Physical Activity Questionnaire (IPAQ); * 18 to 30 old years.

Exclusion criteria

* Body mass index BMI \<18.5kg/m² and \>29.9kg/m²; * Smokers; * Subjects undergoing pharmacotherapies; * Musculoskeletal, metabolic, renal diseases; * Root mean squared standard deviation of R-R intervals \<15 milliseconds.

Design outcomes

Primary

MeasureTime frame
Heart rate variability values (milliseconds)Through study completion, an average of 1 year

Secondary

MeasureTime frame
Systolic and diastolic blood pressure values (mmHg)Through study completion, an average of 1 year
Heart rate values (beats per minute)Through study completion, an average of 1 year

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026