Multitract Percutaneous Nephrolithotomy(PCNL) in Large Renal Stones.

Multitract PCNL as One Step for Management of Large Renal Stones

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05291702

Acronym

PCNL

Enrollment

Registered

2022-03-23

Start date

2022-04-01

Completion date

2024-10-01

Last updated

2022-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Staghorn Calculi

Keywords

PCNL

Brief summary

Investigator aimed to analyze the clinical efficacy and safety of multiple tracts PCNL as one step therapy to treat the staghorn stones or multiple calyceal calculi which are inaccessible by single tract

Detailed description

Staghorn calculi are branched stones either partial or complete occupying the pelvis and one or more of the renal caliceal system that is detected by non contrast computrized tomography (NCCT) and plain on kidney, ureter, urinary bladder (KUB). An untreated staghorn calculus over time can damage the kidney and deteriorate its function and /or cause life threatening sepsis. Total stone clearance is an important goal to eradicate any infective focus, relieve obstruction and preserve the kidney function. Based on American Urological Association (AUA) guideline, PCNL is the most effective, safest and minimally invasive treatment option compared to open surgery

Interventions

PROCEDUREPCNL

Percutaneous nephrolithotomy ( Extraction of the renal stones using the nephroscope/ Ureteroscope )

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Adult patients more than 18 years old. 2. Patients with staghorn stone (partial, complete). 3. Patients with multiple calyceal calculi which are inaccessible by single tract.

Exclusion criteria

1. Patients under 18 years old. 2. Patients with renal anomalies. 3. Patients with only function kidney. 4. Patients with distal ureteric obstruction. 5. Patients with radiolucent stone. 6. Patients with febrile urinary tract infection. 7. Patients with abnormal coagulopathy state. 8. Patients refused to participate in this study. 9. pregnancy. 10. Musculoskeletal deformity.

Design outcomes

Primary

Measure	Time frame	Description
Stone free rate	The participants will be followed for one month after the procedure	Assessment of the instant postoperative stone free rate and after one month from the procedure for all 40 participants using the postoperative non contrast computerized tomography (NCCT )and plain on kidney , ureter, urinary bladder (KUB )

Secondary

Measure	Time frame	Description
Postoperative complications	From the start of the operation and till one month after the patient discharge.	Measuring the postoperative complications rates, classification of the severity of the complications will assess the safety of the procedure.
Operative time	Average of three hours	Measurment of the time from start of the operation till fixation of nephrostomy tube
Postoperative pain	Within 24 hours postoperative and till the patient discharge	Measurment of the postoperative pain score using the Visual analogue scale(VAS) that is divided into mild(1-3), moderate(4-6) and sever(7-10) according to the severity of the pain.
Hospital stay	Average of six days	Postoperative hospital stay of the participants till thier discharge

Contacts

Primary ContactWaleed Mahmoud Abbas, M.Sc

Dr_walidws@yahoo.com+2001009377858

Backup ContactMohamed Ali Zarzour, MD

Dr-mohamedali81@yahoo.com+2001014714142

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026