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Blood Loss Measurement Using Electrical Impedance Tomography

Measurement of Blood Loss Using Electrical Impedance Tomography

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05287334
Enrollment
15
Registered
2022-03-18
Start date
2022-07-01
Completion date
2022-12-31
Last updated
2022-08-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Loss

Keywords

Blood donation, EIT

Brief summary

The project focuses on the possibility of detecting blood loss using electrical impedance tomography. Based on previous animal experiments, it was found that the bolus of saline significantly affects the signal of chest bioimpedance. It is assumed that blood loss of a similar volume will cause a similar signal change with the opposite trend. The aim of this project is to determine whether there is a significant change in the thoracic electrical impedance tomography signal when blood loss is caused by voluntary blood donation.

Detailed description

Electrical impedance tomography is a bedside method of ventilation monitoring. The bioimpedance of the tissue depends, among other things, on its blood content. The area of the chest and especially the lungs is a heavily perfused tissue, which also serves as one of the reservoirs of blood in case of blood loss. It is therefore possible that blood loss will be visible on chest bioimpedance relatively soon. The study will be performed on voluntary blood donors. Blood loss of 450 mL will be caused by the collection of donated blood. During blood collection at the transfusion department, thoracic bioimpedance will be measured using electrical impedance tomography. The resulting signal change will then be analyzed to determine the possibility of detecting and measuring blood loss using electrical impedance tomography.

Interventions

During standard blood donation, donors' chest bioimpedance will be measured using electrical impedance tomography.

Sponsors

Military University Hospital, Prague
CollaboratorOTHER
Czech Technical University in Prague
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE

Intervention model description

Single group assignment. Approx 10-15 voluntary blood donors.

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* voluntary blood donation

Exclusion criteria

* standard

Design outcomes

Primary

MeasureTime frameDescription
Change in chest electrical impedance due to blood loss.Time frame of one voluntary blood donation process (15 min)A change in the electrical impedance of the chest of a voluntary blood donor caused by a blood donation.

Countries

Czechia

Contacts

Primary ContactVaclav Ort, M.Eng.
ortvacla@fbmi.cvut.cz+420 731 577 649

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026