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Ocular Coherence Tomography During Cataract Assessment

Importance of Ocular Coherence Tomography During Cataract Assessment

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05287269
Enrollment
626
Registered
2022-03-18
Start date
2020-11-02
Completion date
2020-11-30
Last updated
2023-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Age Related Macular Degeneration, Cataract Senile, Epiretinal Membrane, Macula Hole, Vitreomacular Traction

Keywords

cataract, macular pathology, ocular coherence tomography

Brief summary

Many patients will have underlying maculopathy present when undergoing cataract surgery, which are not visible on fundoscopy alone. Knowledge of this underlying pathology will allow an improved consenting process and discussion with the patient regarding the risks, visual prognosis and recovery following cataract surgery. Incidental findings in the fellow eye would also allow for improved diagnosis and management of these patients without adding significant additional time to specialist high volume cataract assessment clinics.

Detailed description

The majority of anterior segment pathology may be diagnosed with simple slit lamp biomicroscopy, but posterior segment pathology may not be quite so obvious and can be missed on simple examination especially if a visually significant cataract is present impeding the view. There is also a degree of subjectivity from how much the cataract impairs the vision in comparison to the other elements of the optical pathway within the eye, and whilst there is no single way to evaluate this. Optical coherence tomography (OCT) has been widely present in ophthalmology clinics since it's development 20 years ago although it is not commonly used in all units for the pre-operative assessment of patients referred for cataract surgery in high volume set ups such as the National Health Service (NHS) in the United Kingdom. There may still be reluctance to use OCT in a normal cataract assessment clinic as it may be perceived as an additional step that decreases time efficiency and increase financial investment in the services. In this study we sought to investigate the prevalence of retinal pathology in the patient cohort, the comparison of subjective clinical slit lamp fundoscopy assessmenet with OCT findings and the co-incidental OCT findings in the fellow eye at the time of cataract assessment. OCT was chosen as the most efficient way to support clinicians in the assessment clinics, and to see if the addition of this step added value to the patient consultation and pre-operative assessment.

Interventions

OCT images were recorded as a fast macular radial line scan with captured on either Heidelberg Spectralis (Heidelberg Engineering GmbH, Germany) or Topcon DRI Triton (Topcon Medical Systems inc. USA).

Sponsors

Brighton and Sussex University Hospitals NHS Trust
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
No minimum to 100 Years
Healthy volunteers
Yes

Inclusion criteria

* Patients referred for cataract surgery

Exclusion criteria

* Patients unable to attend the cataract assessment clinic * Morbid patients who cannot be assessed on OCT or slit lamp

Design outcomes

Primary

MeasureTime frameDescription
Incidence of occult macular pathologies in the eye referred for cataract surgeryDuring the cataract assessment clinicComparison of slitlamp biomicroscopy fundus finding with ocular coherence tomography (OCT) scan of the macula

Secondary

MeasureTime frameDescription
Incidence of macular pathologies in the fellow eyeDuring the cataract assessment clinicNoting the incidence of macular pathologies noted on OCT

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026