Bronchial Aspiration
Conditions
Keywords
Bronchial, Aspiration, Bronchoaspiration, Broncho-aspiration, ICU, Intensive Care Unit, Surgical patients, Surgery
Brief summary
Patients of age \>18 yo, admitted to the ICU through the surgery department from 2AUG2021 to 1AUG2022 will be divided into three groups: 1. Patients admitted to the ICU in the first 3-4 months will have their bed head elevated to 15 degrees + H2 blockers administration + mouth wash BID 2. Patients admitted to the ICU in the following 3-4 months will have their bed head elevated to 30 degrees + H2 blockers administration + mouth wash BID 3. Patients admitted in the last 3-4 months will have their bed head elevated to 45 degrees + H2 blockers administration + mouth wash BID. All patients will have their vital signs, BMI, and fluids ins and outs measured every 24 hours until the discharge from the ICU or death. All patients will be evaluated for GI functions (no vomiting, flatus+, bowel movement +, bowel sounds+, and KUB with normal gas distribution pattern) prior to oral intake. Patients in the three groups will be matched by age, sex, and BMI with historical controls with broncho- aspiration (BA) (positive controls) and without BA events (negative controls) from a pool of 20,032 ICU admissions (01JAN2010 to 31DEC2019).
Interventions
OTHERBed Head elevation, H2 blockers and mouth wash
Elevation of the bed head to 15, 30 and 45 degrees, daily H2 blockers administration and mouth wash BID.
OTHERData collection for comparison
Data collection for comparison
Sponsors
Marshall University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age\>18 * All the patients admitted to ICU by surgery department. * Development of aspiration pneumonia in patients admitted to ICU department of VA hospital. * Aspiration Pneumonia development during hospital stay and treating physician indicated the diagnosis of aspiration pneumonia in history and physical exam notes.
Exclusion criteria
* Age \<18 * Patient transferred or admitted to the hospital as a primary diagnosis of aspiration pneumonia (development of aspiration pneumonia prior to admission). * Treating physician not documented aspiration pneumonia in history or physical exam notes. * Drug overdose, seizure or cardiopulmonary arrest prior to hospital admission.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rate of Bronchospiration pneumonia among study participants during their ICU admission | 12 Months | Calculating the number of subjects who developed bronchoaspiration pneumonia compared to the total number of ICU admission |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Determine if there is an association between BA events and death rate in the ICU for the specified time period | 12 Months | Determining the factors impacting the rate of bronchaspiration and the rate of related death |
Countries
United States
Outcome results
None listed