Left Bundle Branch Block (LBBB) on ECG
Conditions
Brief summary
The electromechanical dyssynchrony induced by the presence of LBBB is in some patients, but not all, the cause of progressive left ventricular systolic dysfunction and heart failure. Aims 1. To investigate the clinical, ECG, imaging-derived features in a large cohort of patients affected by LBBB on ECG. 2. To identify predictors of LBBB-induced LV systolic dysfunction and predictors of outcome in this population. 3. To derive data which may have an impact on therapeutic management.
Interventions
DIAGNOSTIC_TESTECG, Echocardiogram, Magnetic resonance
Clinical and instrumental follow-up
Sponsors
Azienda Ospedaliero Universitaria di Sassari
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* LBBB on ECG
Exclusion criteria
* Previous extensive anterior myocardial infarction * Previous cardiac surgery or transcatheter aortic valve implantation (TAVI) * Congenital structural heart disease * Patients implanted with permanent right ventricular stimulation devices and permanent pacing * Denial to consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Left ventricular dysfunction | 20 years | Echocardiographic left ventricular ejection fraction - EF (%) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Adverse cardiovascular events (e.g., heart failure) | 20 years | Heart failure (incidence and prevalence) Hospitalizations due to heart failure MACE |
Countries
Italy
Contacts
Primary ContactGiuseppe D Sanna, MD PhD
Backup ContactGiuseppe D Sanna, MD PhD
Outcome results
None listed