Adult Patients 19 or Older Scheduled for Elective Arthroscopic Meniscectomy
Conditions
Brief summary
This study aims to compare quality of recovery after surgery and anesthesia between patients undergoing arthroscopic meniscectomy under general anesthesia with either propofol or remimazolam based total intravenous anesthesia. This study is a randomized trial with a 50% probability of being assigned to either group. Randomization will be done by an anesthesiologist not involved in anesthesia or postoperative outcome assessment. Patients and the investigator in charge of postoperative outcomes assessment will be blinded to group allocation.
Interventions
DRUGPropofol TIVA
Patients will receive propofol-based TIVA with propofol and remifentanil TCI (target controlled infusion)
DRUGRemimazolam TIVA
Patients will receive remimazolam-based TIVA with remimazolam infusion and remifentanil TCI
Sponsors
Yonsei University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patients 19 or older, ASA class I\ III, * scheduled for arthroscopic meniscectomy under general anesthesia and eligible for LMA use.
Exclusion criteria
* Patient refusal, * patients unable to read consent form, active URI or uncontrolled asthma, * pneumonia, * history of allergies to propofol or benzodiazepines, * decreased liver or kidney function, heart failure of ejection fraction\<55%, * pregnant or breastfeeding patients, * history of substance abuse/addiction
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Quality of Recovery (QoR)-40 questionnaire | Postoperative 24 hours | Quality of recovery assessed with the QoR-40 questionnaire, which is a widely-used, self-rated, self-completed questionnaire for postoperative patients. |
Countries
South Korea
Outcome results
None listed