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A Prospective Multicentre Study Evaluating the Outcomes of the Abdominal Wall Dehiscence Repair Using Posterior Component Separation With Transversus Abdominis Muscle Release Reinforced by a Retro-muscular Mesh - Filling a Step

A Prospective Multicentre Study Evaluating the Outcomes of the Abdominal Wall Dehiscence Repair Using Posterior Component Separation With Transversus Abdominis Muscle Release Reinforced by a Retro-muscular Mesh - Filling a Step

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05278117
Enrollment
202
Registered
2022-03-14
Start date
2014-06-01
Completion date
2022-02-01
Last updated
2022-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal Wall Defect

Keywords

Abdomen burst, Incisional hernia, mesh

Brief summary

Purpose: This study determined the incidence of burst abdomen recurrent (BAR), incisional hernia(IH), and surgical site occurrence (SSO) following burst abdomen surgical treatment after abdominal midline incisions using a posterior component separation(CS) technique with transversus abdominis muscle release (TAR) reinforced by retro-muscular mesh technique. Methods: Between June 2014 and April 2018, 202 patients with grade IA BA (Björck's first classification) were treated in a prospective multiple-center cohort study.

Detailed description

This study determined the incidence of burst abdomen recurrent (BAR), incisional hernia(IH), and surgical site occurrence (SSO) following burst abdomen surgical treatment after abdominal midline incisions using a posterior component separation(CS) technique with transversus abdominis muscle release (TAR) reinforced by retro-muscular mesh technique. Methods: Between June 2014 and April 2018, 202 patients with grade IA BA (Björck's first classification) were treated in a prospective multiple-center cohort study.

Interventions

PROCEDUREoutcomes of complete burst abdomen repair using posterior component separation technique with transversus abdominis muscle release reinforced by sublay mesh

outcomes of complete burst abdomen repair using posterior component separation technique with transversus abdominis muscle release reinforced by sublay mesh

Sponsors

Zagazig University
Lead SponsorOTHER_GOV

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* BA Grade IA according to Björck's initial classification following midline laparotomy from various departments, * ≥ 18 years * both sex * emergency or elective surgery

Exclusion criteria

* BA grade 1B,2,3, and 4 according to Björck's initial classification, * \< 18 years, * primary laparotomy performed through a non-midline incision, open abdomen, * if another laparotomy had been performed between the surgery for BA and the end of the follow-up period, * concomitant intra-abdominal surgery, abdominal complications during BA surgery, * adherent bowel to the defect edge that cannot be separated, * patients lost during follow up, * presence of intra-abdominal contamination that cannot be controlled radiologically, * history of previous BA repair, * stoma exteriorized from the midline primary wound, * temporarily wound closure techniques, * prior abdominal surgeries other than operation resulted in BA, * prior abdominal wall hernia repair with or without mesh, * history of collagen diseases

Design outcomes

Primary

MeasureTime frameDescription
recurrent burst abdomen3.5 yearsincidence of recurrent burst abdomen by %
incisional hernia3.5 yearsincidence of incisional hernia measured by clinical examination and computerized tomography by %

Secondary

MeasureTime frameDescription
incidence of surgical site infection30 daysby %

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 11, 2026