Dementia, Stroke, Acute
Conditions
Brief summary
Some patients develop cognitive decline after a stroke, but we don't always understand the mechanisms. It has been proposed that a proportion of the patients develop an autoimmune immune response, and that this could potentially explain the cognitive decline in some of the patients. The current study aims to investigate this hypothesis in a subgroup of patients with stroke.
Interventions
OTHERAnalysis of post-stroke immune responses
Analysis of immune responses in peripheral blood
Sponsors
University of Oslo
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Stroke \< 72 h * Age \> 18 years
Exclusion criteria
* Brain hemorrhage verified by CT or MRI scan * Previous or present immunological disease or other serious comorbidity * Ongoing immune respons after infection or vaccination \< 1 month * Cognitive without ability to understand and/or give an informed consent to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The B cell and T cell response in peripheral blood | 1 day (subject inclusion) |
Countries
Norway
Contacts
Primary ContactAndreas Lossius, MD, PhD
Outcome results
None listed