Circulating Cathodic Antigen Test Compared to Microscopy for Diagnosis of Urinary Schistosomiasis in Sohag

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05276414

Enrollment

100

Registered

2022-03-11

Start date

2022-03-15

Completion date

2022-10-30

Last updated

2022-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary Schistosomiases

Brief summary

Schistosomiasis is a chronic infection endemic in 74 tropical and sub-tropical countries. Sub-Saharan Africa carries the highest burden (90%) of schistosomiasis which caused by both Schistosoma mansoni and Schistosoma haematobium. The prevalence of Schistosomiasis should be assessed to control of the infection. This is usually achieved through surveys based on the use of traditional parasitological methods as urine filtration for S. haematobium. However, these traditional methods are time consuming, require an experienced technician and multiple samples due to light-infection and irregular shedding. Therefore, the point-of-care Circulating Cathodic Antigen (POC-CCA) urine test has been developed for the diagnosis of S. haematobium infection which is simple, rapid, sensitive and specific assay.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

5 Years to 16 Years

Healthy volunteers

Inclusion criteria

* 100 outpatient children aged between 5 - 16 years

Exclusion criteria

* Outpatient children should not have received schistosomiasis treatment (within the past 6 months) prior to the study

Design outcomes

Primary

Measure	Time frame	Description
to evaluate the accuracy of rapid immunochromatographic assay (POC-CCA) compared with traditional microscopic examination for diagnosis of Schistosoma haematobium infection	16 weeks following the startpoint of the study.	comparing the sensitivity and specificity of rapid immunochromatographic assay with traditional microscopic examination for diagnosis of Schistosoma haematobium infection

Secondary

Measure	Time frame	Description
to estimate the prevalence of Schistosoma haematobium infection in outpatient children in Sohag	16 weeks following the startpoint of the study.	By examining the stool samples of 100 outpatient children and recording the number of cases with Schistosoma haematobium infection.

Countries

Egypt

Contacts

Primary ContactAsmaa K Abd Ellah, lecturer

Asmaakamal@med.sohag.edu.eg01067123632

Outcome results