General Anesthesia
Conditions
Brief summary
The purpose of this study was to determine the appropriate positive end-expiratory pressure (PEEP) using electrical impedance tomography (EIT) in children under general anesthesia and to investigate whether there is a difference between the supine and prone positions.
Interventions
OTHERExploration of optimal PEEP in supine and prone position
1. General anesthesia is done in routine manner 2. A sensor for electrical impedance tomography (EIT) is applied around the patient's chest. 3. In supine position, lung recruitment maneuver is done, followed by decremental PEEP trial. Based on EIT parameter, optimal PEEP which induces minimal overdistension and collapse of lungs is determined. 4. One hour after prone position, optimal PEEP is determined again.
Sponsors
Seoul National University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
No minimum to 1 Years
Healthy volunteers
No
Inclusion criteria
* Children \<= years of age who are scheduled for surgery in the prone position under general anesthesia
Exclusion criteria
* Respiratory distress, bronchopulmonary dysplasia * Pneumothorax * Increased intracranial pressure * History of airway surgery * Cervical or thoracic surgery * Pulmonary hypertension
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Optimal PEEP level at spine position | 10 minutes after intubation (supine) | Optimal PEEP level (cmH2O) determination using electrical impedance tomography at supine position |
| Optimal PEEP level at prone position | 1 hour after prone positioning (prone) | Optimal PEEP level (cmH2O) determination using electrical impedance tomography at prone position |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Dynamic compliance measured using Electrical impedance tomography | until 1 hour after prone positioning | ventilation/pressure (ml/cmH2O) |
| regional ventilation delay measured using Electrical impedance tomography | until 1 hour after prone positioning | ventilation time delay during one breath (no unit) |
| pulmonary opening pressure measured using Electrical impedance tomography | until 1 hour after prone positioning | alveoli opening pressure (cmH2O) |
| atelectasis/overdistension ratio measured using Electrical impedance tomography | until 1 hour after prone positioning | The degree comparing atelectasis and overdistension (no unit) |
Countries
South Korea
Outcome results
None listed