Colorectal Cancer Metastatic, Liver Metastases
Conditions
Brief summary
Retrospective analysis of a prospectively collected database of 170 patients between 2004 and 2020, who underwent liver resections for CRLM (colorectal liver metastases) at The Queen Elizabeth Hospital trying to determine rates and patterns of recurrence following liver resections for CRLM and concurrently, characterise clinical, pathological and treatment-related factors that could function as predictors of recurrence or survival, particularly neoadjuvant chemotherapy and tumour clearance.
Detailed description
This is a descriptive, observational study with retrospective analysis of a prospectively collated database. This database included all patients who underwent curative hepatic resections for CRLM (colorectal liver metastases) at The Queen Elizabeth Hospital (Adelaide, Australia) between December 2004 and October 2020.
Interventions
PROCEDUREHepatectomy
Neoadjuvant treatment
Sponsors
University of Adelaide
Hospital Maciel
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients who underwent a liver resection for CRLM at The Queen Elizabeth Hospital between December 2004 to September 2020
Exclusion criteria
* Patients whose procedures were abandoned due to unresectable tumour burden
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Recurrence | From surgery to recurrence, up to 16 years | Recurrence rate |
| Survival | From surgery to death or end of the study, up to 16 years | up to16 years |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Resection margins | From surgery to death or end of the study, up to 16 years | Resection margins of the liver resection |
| Neoadjuvant Chemotherapy | From surgery to death or end of the study, up to 16 years | Neoadjuvant Chemotherapy (yes or not) |
Outcome results
None listed