Nerve Block, Postoperative Pain
Conditions
Brief summary
Effects of Transabdominal Plain Block and Quadratus Lumborum Block After Laparoscopic Hemicolectomy. The pain relief, bowel function and discharge.
Detailed description
This study is proposed to explore the effects of transabdominal plane block and quadratus lumborum block after laparoscopic hemicolectomy. After laparoscopic hemicolectomy there is a need for good analgesia. When the analgesia is adequate the patients mobilisation, bowel function and discharge is faster. Earlier, epidural block has been used for the analgesia but now the hemicolectomy is laparoscopic procedure and there is no need for central block anymore. Still patients needs opioids after the operation. Because of the opioids side effects, there is a need to find better analgesia methods. In this study investigators compare peripheral nerve blocks, transabdominal plane and quadratus lumborum, for analgesia after laparoscopic hemicolectomy. Also investigators are comparing these analgesia methods and traditional orally analgesics. Patients receive transabdominal or quadratus lumborum block after induction using ropivacaine 5 mg/ml 20 ml per side. The third group is a control group witch analgesia is taken care with traditional orally analgesics. After surgery investigators follow postoperative pain, opiate consumption, bowel function, nausea and mobilisation. Investigators coal is to find if the transabdominal plain block or quadratus lumborum block prefer traditional analgesia methods after laparoscopic hemicolectomy.
Interventions
PROCEDURETransabdominal plane block
Peripheral nerve block
PROCEDUREQuadratus lumborum block
Peripheral nerve block
Sponsors
Tampere University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
Yes
Inclusion criteria
Adult elective hemicolectomy patients
Exclusion criteria
Age under 18 years Complicated diabetes mellitus Lack of finnish language skill and/or co-operation Chronic pain Use of drugs that significantly influences the metabolism of paracetamol or opiate Steroid medication in regular use Significant liver-, lung- or kidney disfunction
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| First need of opiate | 72 hours or until discharge, whichever came first | Time after surgery when the patient needs opiate for the first time |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Post operative pain | postoperatively: at 4 hours, at 8 hours,at 12 hours, at 16 hours, at 20 hours, at 24 hours, at 32 hours, 40 hours, at 48 hours, at 56 hours, at 64 hours, at 72 hours, ones per day after discharge for seven days after operation | Numeric rating scale NRS 0-10, verbally description after discharge |
| Opiate consumption | 72 hours or until discharge, whichever came first | Total opiate consumption after surgery |
| Bowel function | postoperatively: at 4 hours, at 8 hours,at 12 hours, at 16 hours, at 20 hours, at 24 hours, at 32 hours, 40 hours, at 48 hours, at 56 hours, at 64 hours, at 72 hours, ones per day after discharge for seven days after operation | Verbally description: non/gas/function |
| Nausea | postoperatively: at 4 hours, at 8 hours,at 12 hours, at 16 hours, at 20 hours, at 24 hours, at 32 hours, 40 hours, at 48 hours, at 56 hours, at 64 hours, at 72 hours, ones per day after discharge for seven days after operation | Verbally description: yes/no |
Other
| Measure | Time frame | Description |
|---|---|---|
| The State-Trait Anxiety Inventory (STAI) | Baseline and 4 week after operation | — |
| Beck´s depression inventory (BDI) | Baseline and 4 week after operation | — |
| Finnish pain query | Baseline and 4 week after operation | This query has first made by the finnish association for the study of pain. It has been modified for this research. It includes questions how pain infects on the daily life (sleeping, exercising, ability to work, concentration et cetera), how often the pain appears and how intense the pain is (scale 0-10). There is a picture of body where patients marks the pain points. |
Countries
Finland
Contacts
Primary ContactMaija-Liisa Kalliomäki, PhD
Backup ContactJenni Kanerva, PhD
Outcome results
None listed