Chronic Pain
Conditions
Brief summary
Transforaminal injection of chronic radicular lower limb injection by either dexmedetomdine or magnesuim sulfate
Interventions
DRUGepidural transforaminal injection of magnesuim sulfate
transforaminal fluroscopic guided
DRUGepidural transforaminal injection of dexmedtemodine
transforaminal fluroscopic guided
DRUGtransforaminal epidural injection of dexamethasone
transforaminal fluroscopic guided
Sponsors
Minia University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
25 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Age group. 25-75ys old * Both sex. * Lumber disc protrusion at one or two segments on MRI. * Chronic lumbar radiculer pain for more than 6 weeks refractory to * medical treatment for at least 4 weeks. . * Positve leg rising test at 30-70 degrees.
Exclusion criteria
* Diabetic candidates ( type Ior II). * Patient refusal. * MRI with disc sequestration. * Neurological examination revealed foot drop, neuropathic ulcers * Myelopathic or scoliotic patients, . * Coagulopathic patients ( cirrhotic patients, on anti-coagulation )
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| pain score | up to 6 months post-injection | visual analogue pain score. pain value of (0 cm) equals no pain , and value of (10 cm) equals worst pain |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| functional disability | up to 6 months post injection | Modified Oswestry Disability Questionnaire....0% to 20%: minimal disability:....21%-40%: moderate disability: 41%-60%: severe disability...61%-80%: crippled |
| acute complications | 6 hours post-injection | number of patients developed epidural hematoma by magnetic resonance imaging |
Countries
Egypt
Outcome results
None listed