Post Covid Syndrome
Conditions
Brief summary
Coronavirus (19) is a pandemic that affects many countries allover the world. Many patients experienced symptoms as dyspnea and fatigue after their recovery from coronavirus . These symptoms appear to occur regardless the severity of the infection. In addition, many studies reported change in the inflammatory status and immunity in post covid patients. laser acupuncture is a painless noninvasive modality that is used in treating many diseases. laser acupuncture appear to have a role in relieving symptoms, altering inflammatory status and boosting immunity in post covid patients.
Interventions
DEVICElaser acupuncture
gallium-aluminum arsenide diode laser with a continuous wave and a wavelength of 850nm will be used for laser acupuncture. it will be applied for three times per week for 12 weeks
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
30 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* age will be ranged from 30 to 40 years * patients were diagnosed as covid 19 by polymerase chain reaction test using nasopharyngeal swap * patients will be negative polymerase chain reaction test (pcr) with symptoms of dyspnea and fatigue. * patients will be recruited after 2 weeks post the negative pcr * patients who want to participate and complete the study till the end
Exclusion criteria
* patients with photosensitivity * pacemaker plantation pregnant women * BMI more than 30kg/m2 infection or inflammation at the site of acupuncture laser malignancy uncontrolled diabetes psychiatric disorders or mental retardation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change in level of interleukin 4 | after 12 weeks of treatment | BD FACS Canto flow cytometer with BD CBA human th1/th2 cytokine kit will be used |
| change in the level of CD 3 T cells | after 12 weeks of treatment | 5ml of blood will be drawn and serum will be separated. cd3 level will be measured using BD FACS Canto flow cytometer |
| change in the level of cd4 T cells | after 12 weeks of treatment | cd4 will be measured using BD FACS Canto flow cytometer after blood sample will be separated |
| change in level of dyspnea | after 12 weeks of treatment | mMRC scale is a five point scale to detect degree of dyspnea while performing physical activity. it is ranged from 0-4 |
| change in level of interleukin 6 | after 12 weeks of treatment | BD FACS Canto flow cytometer with BD CBA human th1/th2 cytokine kit will be used |
| change in lymphocyte count | after 12 weeks of treatment | BD FACS Canto flow cytometer will be used |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| change in fatigability | after 12 weeks of treatment | chalder fatigue scale is 11 items scale. people of 4 or more are considered meeting the criteria of fatigue |
Contacts
Primary Contactsalma alghitany, PHD degree
Backup Contactsandra girguis, PHD degree
Outcome results
None listed